Detail of > 1218-35-5
- MSDS Download

- CAS Number:
- 1218-35-5
- Name:
Xylometazoline hydrochloride
- Formula:
- C16H25ClN2
- Molecular Structure:

- Synonyms:
- 1H-Imidazole,2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-,monohydrochloride (9CI);2-Imidazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-,monohydrochloride (8CI);Brizolin;Galazolin;Neo-Rinoleina;Neo-Synephrine II;Novorin;Olynth;Otrivin hydrochloride;Otrivine;Otrivine hydrochloride;Therapin;Xymelin;
- Molecular Weight:
- 280.88
- EINECS:
- 214-936-4
- Melting Point:
- 131-133 °C
- Boiling Point:
- 394.2 °C at 760 mmHg
- Flash Point:
- 192.2 °C
- Appearance:
- white to off-white crystalline powder
- Hazard Symbols:
Xn,
Xi- Risk Codes:
- 22-36/37/38
- Safety:
- 36-26Details
- Transport Information:
- UN 2811 6.1/PG 3
- Deleted CAS:
- 28096-10-8|8057-34-9
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Reference
- Stability of pharmaceutical products derived from imidazoline
- Stability of pharmaceutical products derived from imidazoline. VII. Kinetics of the hydrolytic decomposition of xylometazoline hydrochloride. Grabowska, Irena; Rajzer, Danuta (Inst. Technol. Anal. Pharm. Prod., Sch. Med., Gdansk 80-416, Pol.). Acta Pol. Pharm., 41(3), 359-63 (Polish) 1984. CODEN: APPHAX. ISSN: 0001-6837. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 22 The kinetics of xylometazoline-HCl (I-HCl) [1218-35-5] hydrolysis was investigated at pH 0.09-8.0 and at 343-63 K. The lowest hydrolysis rate was noted at pH 1.8. Com. I prepns. (pH 5.7) were stable up to 8 yr at room temp.
- Synthetic ion-exchange resins in the quantitative analysis of pharmaceutical preparations
- Synthetic ion-exchange resins in the quantitative analysis of pharmaceutical preparations. XV. Determination of imidazoline, pyrazoline, and pyridine derivatives in various forms of simple pharmaceuticals. Jarzebinski, Jerzy (Inst. Drug Sci., Sch. Med., Warsaw, Pol.). Acta Pol. Pharm. 1641-74-3 and 68-89-3 which are cas registry numbers are also used here., 33(5), 599-604 (Polish) 1976. CODEN: APPHAX. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Solns. contg. the drugs to be assayed were passed through columns packed with Amberlite IR 20 in the Zn2+ or H+ form and the eluate was analyzed for Zn2+ or H+ by complexometric or alkalimetric titrn., resp. The method secured high-accuracy results in detg. benzydamine-HCl [132-69-4], bis(4-pyridylmethyl)amine citrate [22164-96-1], methylphenidate-HCl [298-59-9], phenazopyridine-HCl [136-40-3], tolazoline-HCl [59-97-2], nicametate dihydrogen citrate [1641-74-3], noramidopyrine Na methanesulfonate [68-89-3], tymazoline-HCl [28120-03-8], pyridoxinium chloride [58-56-0], and xylometazoline-HCl [1218-35-5] in tablets, dragees, and solns. .
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