Detail of "123-78-4"

Reference

Selective enrichment of phytosphingosine in glycosphingolipids of isolated human thyrocytes as compared to the whole thyroid

Selective enrichment of phytosphingosine in glycosphingolipids of isolated human thyrocytes as compared to the whole thyroid. Bouchon, B.; Portoukalian, J.; Orgiazzi, J.; Bornet, H. (Lab. Immunol., Cent. Leon Berard, Lyon 69373, Fr.). Biochem. 554-62-1 and 123-78-4 which are cas registry numbers are also used here. Biophys. Res. Commun., 143(3), 827-31 (English) 1987. CODEN: BBRCA9. ISSN: 0006-291X. DOCUMENT TYPE: Journal CA Section: 13 (Mammalian Biochemistry) The glycosphingolipids of isolated human thyrocytes were analyzed. As compared to the total thyroid gland, the pattern of gangliosides was similar, whereas the neutral glycolipid profile was quite different, with glucosylceramide as the major glycosphingolipid of thyrocytes. Moreover, this glucosylceramide contains almost exclusively phytosphingosine, which is only a minor component in the long-chain bases of the glycosphingolipids extd. from the whole thyroid gland. .

Isolation and characterization of a novel 2-aminoethylphosphonylglycosphingolipid from the sea hare, Aplysia kurodai

Isolation and characterization of a novel 2-aminoethylphosphonylglycosphingolipid from the sea hare, Aplysia kurodai. Araki, Shigeko; Abe, Sachiko; Ando, Susumu; Fujii, Naoyuki; Satake, Mei (Brain Res. Inst., Niigata Univ., Niigata 951, Japan). J.Chemical with cas number 123-78-4 also plays role. Biochem. (Tokyo), 101(1), 145-52 (English) 1987. CODEN: JOBIAO. ISSN: 0021-924X. DOCUMENT TYPE: Journal CA Section: 12 (Nonmammalian Biochemistry) A novel phosphonoglycosphingolipid named SGL-I' contg. 1 mol. of 2-amino-ethylphosphonate residue was isolated from the skin of A. kurodai by 2 silicic acid chromatog. systems. Data obtained on methanolysis, permethylation, mild acid hydrolysis, and HF treatment combined with TLC, gas-liq. chromatog., gas chromatog.-mass spectrometry, and 1H-NMR showed that this glycolipid was 3-O-MeGalb1?3GalNAca1?3[6'-O-(2-aminoethylphosphonyl)Gala1 ?2]Gab1?4Glcb1?1Ceramide. Palmitic acid, octadeca-4-spingenine and anteiso-nonadeca-4-sphingenine are its major aliph. components. The new glycolipid has essentially the same structure as another major phosphonoglycospingolipid in the skin of Aplysia, SGL-II, that contains 2 mol. of 2-aminoethylphosphonate residue, which suggests a metabolic relationship between the two. .