Detail of "1236-99-3"

CAS Number:
1236-99-3
Name:
10H-Phenothiazine-10-propanamine,2-methoxy-N,N,b-trimethyl-,hydrochloride (1:1), (bR)-
Superlist Name:
Levomepromazine hydrochloride
Molecular Structure:
Formula:
C₁₉H₂₄N₂OS^.HCl
Molecular Weight:
364.9326
Synonyms:
10H-Phenothiazine-10-propanamine,2-methoxy-N,N,b-trimethyl-,monohydrochloride, (R)-;10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,b-trimethyl-, monohydrochloride, (bR)- (9CI);Phenothiazine,10-[3-(dimethylamino)-2-methylpropyl]-2-methoxy-, monohydrochloride, (-)-(8CI);(-)-Methotrimeprazine hydrochloride;Levomepromazine hydrochloride;Levomepromazinium chloride;Levopromazine hydrochloride;Methotrimeprazinehydrochloride;Neurocil;
EINECS:
214-978-3
Boiling Point:
468 °C at 760 mmHg
Flash Point:
236.8 °C

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levomepromazine hydrochloride

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Thermal behavior of psychotherapeutic compounds: Thermal behavior of psychotherapeutic compounds.Some chemicals with cas registry numbers like 113-59-7 and 69-09-0 are also used. II. Amitriptyline hydrochloride, trihexyphenidyl hydrochloride, chlorpromazine hydrochloride, levomepromazine hydrochloride, and chlorprothixene. Masse, J.; Chauvet, A.; Malaviolle, R.; Sabon, F. (Lab. Chim. Gen. Miner., Fac. Pharm., Montpellier, Fr.). Trav. Soc. Pharm. Montpellier, 36(3), 209-17 (French) 1976. CODEN: TSPMA6. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 69, 75 Thermal properties were detd. for chlorprothixene [113-59-7], chlorpromazine-HCl [69-09-0], trihexyphenidyl-HCl [52-49-3], amitriptyline-HCl [549-18-8], and levomepromazine-HCl [1236-99-3] by thermomicroscopy and differential calorimetry. The melting enthalpy for each compd. was detd. Several compds. were polymorphic. .

Anticholinergic and cardiodepressive effects of levomepromazine and two of its metabolites on isolated rat atria: Anticholinergic and cardiodepressive effects of levomepromazine and two of its metabolites on isolated rat atria. Passwal, Masjedi; Dahl, Svein G.; Refsum, Helge (Inst. Pharmacol., Univ. Oslo, Oslo, Norway). Eur. J. Pharmacol., 40(2), 249-54 (English) 1976.Several substances with their cas registry numbers 61733-92-4 and 51-84-3 may be metioned in this study. CODEN: EJPHAZ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) The effects of monodesmethyl levomepromazine-HCl [61733-92-4] on effective refractory period (ERP) threshold for elec. stimulation and contractile force on isolated rat atria were compared to the effects of levomepromazine-HCl (I) [1236-99-3] and levomepromazine sulfoxide-HCl [60119-90-6]. All agents caused an apparently dose-dependent increase in ERP, and antagonized acetylcholine [51-84-3]-induced redns. in ERP. I and monodesmethyl levomepromazine decreased excitability and contractile force to a similar extent. .