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1256580-46-7

Basic Information
CAS No.: 1256580-46-7
Name: 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
Article Data: 22
Molecular Structure:
Molecular Structure of 1256580-46-7 (9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile)
Formula: C30H34N4O2
Molecular Weight: 482.62
Synonyms: 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile;
EINECS: 821-541-6
Density: 1.28
Boiling Point: 722.5±60.0 °C(Predicted)
PSA: 72.36000
LogP: 4.77618
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CH5424802 is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. CH5424802 have been clinically evaluated for the treatment of patients with ALK-driven tumors.