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Detail of "127-33-3"

  • MSDS Download
  • CAS Number:
  • 127-33-3
  • Name:

  • 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,(4S,4aS,5aS,6S,12aS)-

  • Molecular Structure:
  • Formula:
  • C21H21 Cl N2 O8
  • Molecular Weight:
  • 464.89
  • Synonyms:
  • 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-(8CI); 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,[4S-(4a,4aa,5aa,6b,12aa)]-; 6-Demethyl-7-chlorotetracycline;6-Demethyl-7-chlortetracycline; 6-Demethylchlorotetracycline;6-Demethylchlortetracycline;7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide;7-Chloro-6-demethyltetracycline; Bioterciclin; Chlortetracycline, 6-demethyl-;DMCT; DMCT (antibiotic); Deganol; Demeclocycline; Demeclor;Demethylchlorotetracycline; Demethylchlortetracyclin;Demethylchlortetracycline; Demetraclin; Diuciclin; Elkamicina; Ledermycin;Mexocine; Novotriclina; Perciclina; Periciclina; RP 10192; Sumaclina;Tri-demethylchlortetracycline
  • Density:
  • 1.75g/cm3
  • Boiling Point:
  • 684.5°Cat760mmHg
  • Flash Point:
  • 367.8°C
  • Safety:
  • Poison by intravenous and intraperitoneal routes. Human systemic effects by ingestion: diabetes insipidus, urine volume increase, other changes in urine composition, dermatitis, changes in the nails, allergic rhinitis, serum sickness, effects on cyclic nucleotides. Human reproductive effects by an unspecified route: postnatal measures or effects on newborn. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Cl− and NOx. Details
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CAS No.127-33-3 demeclocycline

Assay:99%  Appearance:powder  Package:25kg/drum

Supplier:HANGZHOU TOYOND BIOTECH CO., LTD [ China (Mainland)]

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CAS No.127-33-3 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,(4S,4aS,5aS,6S,12aS)-

Assay:EP

Supplier:Changzhou Highassay Chemical Co., Ltd [ China (Mainland)]

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Address:XIXIASHU TOWN, XINBEI DISTRICT, CHANGZHOU, JIANGSU

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CAS No.127-33-3 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,(4S,4aS,5aS,6S,12aS)-

Demeclocycline CAS: 64-73-3 Molecular formula: C21H21ClN2O8 Molecular weight: 464.85 Purity: 98%

Supplier:Wuhan Hezhong Chemical Manufature Co.,Ltd [ China (Mainland)]

610Integral
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Address:496 zhongshan road, Wuhan, Hubei, China(hzchemsales04(at)gmail dot com )

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CAS No.127-33-3 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,(4S,4aS,5aS,6S,12aS)-

Supplier:Hebei YuZe Chemical Technology Co., Ltd. [ China (Mainland)]

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250

Tel:86-0311-87319676

Address:Tianshan Industrial Park, Xiangjiang Road 319, East Development Zone, Hebei, Shijiazhuang

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Reference

Stability of frozen rat plasma containing different antibiotics
Stability of frozen rat plasma containing different antibiotics. Berti, Maria A.; Maccari, Mario (Lab. Microbiol. Pharmacol., Proter S. 61-33-6 and 15686-71-2 are cas registry numbers. These chemicals are also mentioned in this article.p.A., Opera, Italy). Antimicrob. Agents Chemother., 8(6), 633-7 (English) 1975. CODEN: AMACCQ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) The antibiotic activity was detd. at different intervals of time on plasma samples, taken from rats treated with a certain no. of commonly used antibiotics, and kept at -20.degree. up to 8 weeks. The results of microbiol. assays demonstrate that the stability of the antibiotics in the frozen plasma decreases in the following order: oxytetracycline [79-57-2] > cephalexin [15686-71-2], streptomycin [57-92-1], erythromycin [114-07-8] > demeclocycline [127-33-3] > ampicillin [69-53-4], amoxycillin [26787-78-0] > penicillin G [61-33-6], cephaloridine [50-59-9], rolitetracycline [751-97-3], and tetracycline [60-54-8]. .
Chemistry and formation of N-nitroso compounds: tetracyclines
Chemistry and formation of N-nitroso compounds: tetracyclines. Roeper, H.Several substances are used for example 10118-90-8 and 564-25-0 which are their cas registry numbers. (Inst. Org. Chem. Biochem., Univ. Hamburg, Hamburg 2000/13, Fed. Rep. Ger.). Nitrosamin-Probl., Ber. Abschlusskolloq., Meeting Date 1982, 223-30. Edited by: Preussmnan, Rudolf. Verlag Chem.: Weinheim, Fed. Rep. Ger. (German) 1983. CODEN: 50VIAQ. DOCUMENT TYPE: Conference CA Section: 1 (Pharmacology) Section cross-reference(s): 17 Achromycin [60-54-8], Aureomycin [57-62-5], anhydroaureomycin [4497-08-9], ledermycin [127-33-3], minocycline [10118-90-8], oxytetracycline [79-57-2], and doxycycline [564-25-0] were tested in simulated human gastric juice in the presence of NaNO2 and NaSCN for their ability to form potentially carcinogenic dimethylnitrosamine (DMNA) [62-75-9]. Of the tetracyclines tested, DMNA was formed from anhydroaureomycin, minocycline, oxytetracycline, and doxycycline. Ascorbic acid [50-81-7] effectively inhibited the formation of DMNA. Structure relations with respect to DMNA formation are discussed. .
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