Reference

Water-soluble sulfonamides for sunscreens

Water-soluble sulfonamides for sunscreens. (Riese, Dr., und Co., Fed. Rep. Ger.). Ger. Offen. DE 3230592 A1 23 Feb 1984, 11 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: A61K007-42; A61K031-18; A61K031-63. APPLICATION: DE 82-3230592 17 Aug 1982. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Sunscreen emulsions that inhibit burning without inhibiting tanning contain 1-5% of a H2O-sol. sulfonamide, such as 6-(sulfanilamido)-2,4-dimethylpyrimidine (I) [515-64-0] or 3,4-dimethyl-5-sulfanilamidoisoxazole (II) [127-69-5]. The emulsion also can contain panthenol [81-13-0]. A sunscreen contained ethoxylated fatty alc. 1.5, ethoxylated fatty alc. sulfonate 1.0, cetyl alc. 2.0, iso-Pr palmitate 1.5, methylsilicone oil 0.5, C14-20 fatty alc. 0.33, panthenol 2.4 allantoin 0. 515-64-0 and 81-13-0 which are cas registry numbers of substances are two of reagents here.4, H2O-sol. sulfonamide 3, preservatives 0.04-0.2, nonphotosensitizing perfume 0.2-0.3, in H2O to 100%. .

Thermal analysis of pharmaceutical compounds

Thermal analysis of pharmaceutical compounds. IV. Evaluation of sulfonamides by thermal analysis. Khattab, Fatma I.; Amer, M. M.; Hassan, Nagiba Y.Chemicals with cas numbers 72-14-0 and 57-67-0 also play role. M. (Fac. Pharm., Cairo Univ., Cairo, Egypt). J. Therm. Anal., 25(2), 367-75 (English) 1982. CODEN: JTHEA9. ISSN: 0368-4466. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Sulfonamides can be detd. by means of their characteristic endothermic DTA peaks (melting peaks), for which the area changes linearly with the amt. The method is suitable for the detn. of 30-100 mg of sulfathiazole [72-14-0], sulfisomidine [515-64-0], sulfaguanidine [57-67-0], sulfacetamide [144-80-9] and sulfamethoxypyridazine [80-35-3] with reasonable accuracy. For sulfisoxazole [127-69-5], 2 peaks are used for detn: an endothermic peak to det. 30-100 mg, and an exothermic one to det. 6-30 mg. Mean recoveries were 98.5-100.9%. .