Detail of "128-09-6"

CAS Number:
128-09-6
Name:
N-Chlorosuccinimide
Molecular Structure:
Formula:
C₄H₄ClNO₂
Molecular Weight:
133.53 .
Synonyms:
2,5-Pyrrolidinedione,1-chloro-;Succinimide,N-chloro- (6CI,7CI,8CI);1-Chloro-2,5-pyrrolidinedione;Chlorosuccinimide;Succinchlorimide;Succinic N-chloroimide;
EINECS:
204-878-8
Density:
1.5 g/cm³
Melting Point:
144-148 °C
Boiling Point:
200.5 °C at 760 mmHg
Flash Point:
75.1 °C
Solubility:
Slightly soluble
Appearance:
white to off-white crystalline powder
Hazard Symbols:
Xi,C
Risk Codes:
22-34
Safety:
26-36/37/39-45-37/39 Details
Transport Information:
UN 3261 8/PG 2

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Reference

Disinfecting with chlorine-containing biocide dispensed from shaped polymeric body: Disinfecting with chlorine-containing biocide dispensed from shaped polymeric body. Theeuwes, Felix (Alza Corp., USA). U.S. US 4418038 A 29 Nov 1983, 8 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A01N025-08; A01N029-00. NCL: 422037000. APPLICATION: US 81-317528 2 Nov 1981. 128-09-6 which is the cas registry number is also used here. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) A device for dispensing a biocide contg. Cl, useful for disinfecting an environment or an article of commerce, comprises a polymer contg. a Cl-donating reagent and a Cl-accepting reagent that on their release from the polymer reacts in the presence of moisture to produce a chlorinous biocide. The dispensing device consists essentially of a body shaped, sized, and adapted for placement in an environment of use. The device has 31 surface for releasing its contents and can have any preselected geometric shape. The device can be made from commonly used (erodible) polymers. The Cl-donating compds. are such as N-chlorosuccinimide [128-09-6], N-chlorourea [3135-74-8], N-chloroacetylurea [4791-21-3], etc., and Cl-accepting reagents include NH4Cl, (NH4)2SO4, sulfamic acid, EtNH2, morpholine, etc. .

N-Halo derivatives VI: N-Halo derivatives VI. Microbiological and chemical evaluations of 3-chloro-2-oxazolidinones. Kosugi, Masanori; Kaminski, James J.; Selk, Sally H.; Pitman, Ian H.; Bodor, Nicolae; Higuchi, Takeru (Interx Res. Corp., Lawrence, Kans., USA). J. Pharm. Sci., 65(12), 1743-6 (English) 1976. CODEN: JPMSAE. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Section cross-reference(s): 28, 63 Comparative antimicrobial activity of 3-chloro-2-oxazolidinone (I) [33779-50-9], 3-chloro-4-methyl-2-oxazolidinone (II) [33744-01-3], 3-chloro-4,4-dimethyl-2-oxazolidinone (III) [58629-01-9], and N-chlorosuccinimide (IV) [128-09-6] was evaluated in aq. buffers in the absence and presence of 5% horse serum. All 4 compds. had similar bactericidal activity in the absence of horse serum, but I and III had superior activity relative to IV when serum was present. 497-25-6 which is the cas registry number is also used here. III was considerably more stable with respect to loss of pos. chlorine and bactericidal activity than I and II when stored in 0.1 M NaH2PO4 buffered to pH 7.0 at 40.degree.. Thus, III is potentially the most useful bactericidal agent of those evaluated. The chlorine potentials of I, II, and III, the rate consts. for transfer of pos. chlorine from I and III to morpholine in aq. solns., and the hydrolytic stabilities of I and III with respect to loss of pos. chlorine were evaluated. These data, together with previously calcd. data for IV, are used to rationalize the obsd. bactericidal activities. .

Detail of "128-09-6"

N-Chlorosuccinimide

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Reference