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CAS No.: | 129580-63-8 |
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Name: | Satraplatin |
Article Data: | 2 |
Molecular Structure: | |
Formula: | C10H22Cl2N2O4Pt |
Molecular Weight: | 500.282 |
Synonyms: | Platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-, (OC-6-43)-;Cyclohexanamine,platinum complex;BMS 182751;BMY 45594;JM 216;POplat; |
Boiling Point: | 134.5 °C at 760 mmHg |
Flash Point: | 32.2 °C |
PSA: | 81.86000 |
LogP: | 3.70610 |
Molecular Formula: C10H22Cl2N2O4Pt
Molecular Weight: 500.29
Flash Point: 32.2 ºC
Product Name: Satraplatin
CAS Registry Number: 129580-63-8
Boiling Point: 134.5 ºC at 760 mmHg
Synonyms: Bis(acetato-o)amminedichloro(cyclohexanamine)-pt ; Platinum (lv) cis-dichloro-trans-bis(acetato-o)ammine(cyclohexanamine) ; Satraplatin ; JM 216
Following is the molecular structure of Satraplatin (129580-63-8):
Satraplatin (129580-63-8) is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. It has not yet received approval from the U.S. Food and Drug Administration. First mentioned in the medical literature in 1993 .Satraplatin is the first orally active platinum-based chemotherapeutic drug; other available platinum analogues—cisplatin, carboplatin, and oxaliplatin—must be given intravenously.
It is made available in the United States jointly by Spectrum Pharmaceuticals and GPC Biotech under the name SPERA (Satraplatin Expanded Rapid Access)
Satraplatin (129580-63-8) has also been used in the treatment of lung and ovarian cancers. The mode of action is that the compound binds to the DNA of cancer cells rendering them incapable of dividing