Detail of "130312-02-6"

CAS Number:
130312-02-6
Name:
1-Pyrrolidinecarboxylicacid, 3-oxo-, phenylmethyl ester
Superlist Name:
1-N-Cbz-3-pyrrolidinone
Molecular Structure:
Formula:
C₁₂H₁₃NO₃
Molecular Weight:
219.24
Synonyms:
1-Benzyloxycarbonyl-3-pyrrolidinone;3-Oxopyrrolidine-1-carboxylic acid benzyl ester;Benzyl 3-oxopyrrolidine-1-carboxylate;N-Benzyloxycarbonyl-3-pyrrolidinone;Phenylmethyl3-oxo-1-pyrrolidinecarboxylate;
Density:
1.255 g/cm³
Melting Point:
45-47 ºC
Boiling Point:
370.2 ºC at 760 mmHg
Flash Point:
177.7 ºC
Hazard Symbols:
Xn
Risk Codes:
22-40
Safety:
23-24/25-36/37 Details

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CAS No.130312-02-6 1-N-Cbz-3-pyrrolidinone

Chemdraw name:3-Oxo-pyrrolidine-1-carboxylic acid benzyl ester；CAS Number: 130312-02-6；Formula: C12H13NO3；FW: 219.24；Appearrance：Buff solid， purity>97%，in store

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benzyl 3-oxopyrrolidine-1-carboxylate

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Reference

Preparation and in vitro and in vivo evaluation of quinolones with selective activity against Gram-positive organisms: Preparation and in vitro and in vivo evaluation of quinolones with selective activity against Gram-positive organisms. Cooper, Curt S.; Klock, Pamela L.; Chu, Daniel T.In this study， 177-11-7 and 130312-02-6 are also used. W.; Hardy, Dwight J.; Swanson, Robert N.; Plattner, Jacob J. (Anti-Infect. Res. Div., Abbott Lab., Abbott Park, IL 60064-3500, USA). J. Med. Chem., 35(8), 1392-8 (English) 1992. CODEN: JMCMAR. ISSN: 0022-2623. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 10 A series of quinolone derivs. I (R = 2,4-F2C6H3, cyclopropyl, X = CH, N, CF, Y = O, NOH, NOMe, n = 1, 2) were prepd. which contained oximes or substituted oximes. Thus, condensing azadioxaspirononane or -decane II with quinone derivs. III (Z = F, Cl) and hydrolysis gave I (Y = O) which were converted to the oximes. I showed in vivo activity against Staphylococcus aureus. I (R = 2,4-F2C6H3, X = CH, Y = NOH, n = 2) had in vivo activity against Streptococcus pneumoniae. .

Detail of "130312-02-6"

1-Pyrrolidinecarboxylicacid, 3-oxo-, phenylmethyl ester

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Reference