Detail of "13111-57-4"

CAS Number:
13111-57-4
Name:
4H-1-Benzopyran-4-one,5,7-dihydroxy-3-(4-hydroxyphenyl)-8-methoxy-
Molecular Structure:
Formula:
C16H12 O6
Molecular Weight:
300.2629
Synonyms:
Isoflavone,4',5,7-trihydroxy-8-methoxy- (7CI,8CI); Pseudotectorigenin (6CI);Isotectorigenin; Isotectrigenin; y-Tectorigenin
Density:
1.512 g/cm³
Boiling Point:
578.1 °C at 760 mmHg
Flash Point:
220.9 °C

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Isoflavonoids genistein, psi-tectorigenin, and orobol increase cytoplasmic free calcium in isolated rat hepatocytes: Isoflavonoids genistein, psi-tectorigenin, and orobol increase cytoplasmic free calcium in isolated rat hepatocytes. Tomonaga, Takeshi; Mine, Tetsuya; Kojima, Itaru; Taira, Masanori; Hayashi, Haruyuki; Isono, Kaichi (Sch. Med., Chiba Univ., Chiba 280, Japan). Biochem. Biophys. Res. Commun., 182(2), 894-9 (English) 1992. CODEN: BBRCA9. ISSN: 0006-291X. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 13 Isoflavonoid compds. genistein, psi-tectorigenin, and orobol have been implicated as inhibitors of tyrosine-specific protein kinase and phosphatidylinositol turnover. These compds.Several substances with their cas registry numbers 446-72-0 and 13111-57-4 may be metioned in this study. have been frequently used as a pharmacol. tool to assess signal transduction pathways in various cell systems. In the course of analyzing signaling pathways in rat hepatocytes, the authors obtained an unexpected finding that these compds. transiently increase cytoplasmic free calcium. Since the Ca2+ mobilizing effect was obsd. in 1 mM calcium-contg. buffer, the source of the Ca2+ may be intracellular stores. Thus, when interpreting data obtained using these compds., caution is needed. .