Detail of "13224-99-2"

CAS Number:
13224-99-2
Name:
a-D-Glucopyranose,4,6-O-ethylidene-
Superlist Name:
4,6-O-Ethylidene-alpha-D-glucose
Molecular Structure:
Formula:
C8H14 O6
Molecular Weight:
206.19
Synonyms:
Glucopyranose,4,6-O-ethylidene-, a-D- (8CI); Pyrano[3,2-d]-1,3-dioxin, a-D-glucopyranose deriv.; 4,6-O-Ethylidene a-D-glucopyranose;4,6-O-Ethylidene-a-D-glucose;Ethylidene glucose; NSC 89726
EINECS:
236-198-2
Melting Point:
168-170 ºC
Safety:
WGK Germany 3

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4,6-O-Ethylidene-D-glucose

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Sugars and sugar derivatives which inhibit the short-circuit current of the everted small intestine of the rat: Sugars and sugar derivatives which inhibit the short-circuit current of the everted small intestine of the rat. Muflih, I. W.; Widdas, W. F. (Dep. Physiol., Bedford Coll., London, Engl.). J. Physiol. (London), 263(2), 101-14 (English) 1976.Several reagents with their cas registry numbers 63-42-3 and 146-72-5 are used here. CODEN: JPHYA7. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Ethylidene glucose (I) [13224-99-2] (.ltoreq.20mM) and benzylidene glucose (II) [25152-90-3] (.ltoreq.5mM) reduced the short-circuit current generated in everted rat intestine by transportable sugars such as galactose [59-23-4] (5.5mM) and 3-O-methyl glucose [146-72-5] (12mM). I and II also reduced the basal short-circuit current established by the everted intestine in a sugar-free Krebs soln. Both types of inhibition approached satn. at the higher concns. used. Similar inhibitory properties were shown by mannose [3458-28-4], lactose [63-42-3], and cellobiose [528-50-7]. These compds. possibly react with the sites for active hexose transfer without translocation by the system, and the significance of the results is discussed in this context. .

The effects of transportable ('blockers') and nontransportable inhibitors ('lockers') on rat transjejunal potential difference in vivo: The effects of transportable ('blockers') and nontransportable inhibitors ('lockers') on rat transjejunal potential difference in vivo. Levin, R. J.; McGourty, J. (Dep. Physiol., Univ. Sheffield, Sheffield, Engl.). J. Physiol. (London), 263(1), 226P-227P (English) 1976. CODEN: JPHYA7. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Rat basal transjejunal p.d. was not depressed by 'lockers'; e.g. 25mM ethylidene glucose [13224-99-2], of the electrogenic hexose transfer system. In contrast, the 'blocker' arbutin [497-76-7] increased the p.d. and displayed electrogenic transport, the increases in p.d. showing satn. kinetics, apparent Km 10-12mM and max. p.d. 3-5 mV. The 'locker' phloridzin [60-81-1] behaved anomalously as a 'blocker', stimulating basal p.d. 60-81-1 and 25152-90-3 which are cas registry numbers of substances are two of reagents here. in 52% of rats and showing satn. kinetics with an apparent Km of 2-3mM and a max. p.d. of 2-3 mV. .