Reference

Study of the selective toxicity of sec-butylamine for fungi

Study of the selective toxicity of sec-butylamine for fungi. Eckert, J. W.; Bretschneider, Brigitte; Rahm, M. L. (Univ. California, Riverside, Calif., USA). Dokl. Soobshch. - Mezhdunar. Kongr. Zashch. Rast., 8th, Volume 3, Issue 2, 666-7. Orgkom. VIII Mezhdunar. Kongr. Zashch. Rast.: Moscow, USSR. (Russian) 1975. CODEN: 37MVAB. DOCUMENT TYPE: Conference CA Section: 5 (Agrochemicals) Section cross-reference(s): 10 (+)-Sec-butylamine [513-49-5] and (-)-sec-butylamine [13250-12-9] were readily absorbed by Penicillium digitatum mycelia both under cultural conditions or when the mycelia were incubated with the compds. Both compds. accumulated to high levels by the fungus, and were readily released back into the medium. Since it is known that the (-)-isomer but not the (+)-isomer is toxic toward the fungus, the toxicity is thus not related to the accumulation rate. Primary amines such as MeNH2 [74-89-5], EtNH2 [75-04-7], PrNH2 [107-10-8], and BuNH2 [109-73-9] were readily metabolized by the fungus, while branched amines such as iso-PrNH2 [75-31-0], 1-methylbutylamine [625-30-9], and sec-butylamine were more resistant to metabolic breakdown.

Gas-phase enantioselectivity of chiral amido[4]resorcinarene receptors

All Rights Reserved. Gas-phase enantioselectivity of chiral amido[4]resorcinarene receptors. Botta, Bruno; Caporuscio, Fabiana; D'Acquarica, Ilaria; Delle Monache, Giuliano; Subissati, Deborah; Tafi, Andrea; Botta, Maurizio; Filippi, Antonello; Speranza, Maurizio (Dipartimento degli Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Universita "La Sapicnza", Rome 00185, Italy). Chemistry--A European Journal, 12(31), 8096-8105 (English) 2006 Wiley-VCH Verlag GmbH & Co. KGaA. CODEN: CEUJED. ISSN: 0947-6539. DOCUMENT TYPE: Journal CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 22 Diastereomeric proton-bound [1×H×AA]+ complexes between selected amino acids [1 = chiral amido[4]resorcinarene receptor; H = proton; AA = L- and D-Phg, Phe, Trp, Tyr(Me), Thr, alloThr, DOPA] display a significant enantioselectivity when undergoing loss of amino acid guest mol. by exchanging with (R)- and (S)-2-aminobutanes (B) in the gas phase. The enantioselectivity of the B-to-AA displacement is ascribed to a combination of thermodn. and kinetic factors related to the structure and the stability of the diastereomeric [1×H×AA]+ complexes and of the reaction transition states. The results of the present and previous studies allow classification of the [1×H×AA]+ complexes in three main categories wherein: (i) guest AA does not present any addnl. functionalities besides the amino acid one (Ala, Phg, and Phe); (ii) guest AA presents an addnl. alc. function (Ser, Thr, and alloThr); and (iii) guest AA contains several addnl. functionalities on its arom. ring [Tyr, Tyr(Me), Trp, and DOPA].In this experiment, several chemicals are used like 918875-68-0 and 13250-12-9 Each category exhibits a specific enantioselectivity depending upon the predominant [1×H×AA]+ structures and the orientation of the 2-aminobutane reactant in the relevant adducts obsd. The results may contribute to the understanding of the exceptional selectivity and catalytic properties of enzyme mimics towards unsolvated biomols. .