Detail of > 132866-11-6
- CAS Number:
- 132866-11-6
- Name:
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1)
- Superlist Name:
- Lercanidipine hydrochloride
- Formula:
- C36H42ClN3O6
- Molecular Structure:
![Molecular Structure of 132866-11-6 (3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1))](http://www.lookchem.com/300w/2010/0618/132866-11-6.jpg)
- Synonyms:
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester,monohydrochloride (9CI);Cardiovasc;Carmen;Corifeo;Lercadip;Lercan;Lercapin;Lercaton;Lerkamen;Lerzam;R 75;Rec15/2375;Renovia;Vasodip;Zandip;Zanicor;
- Molecular Weight:
- 648.19
- Melting Point:
- 175-177 °C
- Boiling Point:
- 712.5 °C at 760 mmHg
- Flash Point:
- 384.7 °C
- Appearance:
- pale-yellow powder
- Hazard Symbols:
T- Risk Codes:
- 25
- Safety:
- 36/37-45Details
- Transport Information:
- UN 2811
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Reference
- Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
- Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation. 132866-11-6 is the cas registry number. This chemical is also mentioned in this article. Bonifacio, Fausto; Campana, Francesco; De Iasi, Gianluca; Leonardi, Amedeo (Recordati Ireland Limited, Ire.). PCT Int. Appl. WO 2003014084 A1 20 Feb 2003, 93 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: C07D211-90. ICS: A61K031-44; A61P009-12. APPLICATION: WO 2002-EP8699 5 Aug 2002. PRIORITY: IT 2001-MI1726 6 Aug 2001. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 27 The invention describes novel lercanidipine (I) crude forms (A) and (B), novel I-HCl cryst. forms I and II obtained from crude forms, pharmaceutical, antihypertensive compns. contg. as active agent at least one of the I-HCl cryst. forms I and II and methods of use.In this study，132866-11-6 is also used. I-HCl was prepd. and the cryst. forms obtained by crystn. from various solvents. The bioavailability of the various forms was also detd. ..
- Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
- Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation. 132866-11-6 is the cas registry number. This chemical is also mentioned in this article. Bonifacio, Fausto; Campana, Francesco; De Iasi, Gianluca; Leonardi, Amedeo (Recordati Ireland Limited, Ire.). PCT Int. Appl. WO 2003014084 A1 20 Feb 2003, 93 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: C07D211-90. ICS: A61K031-44; A61P009-12. APPLICATION: WO 2002-EP8699 5 Aug 2002. PRIORITY: IT 2001-MI1726 6 Aug 2001. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 27 The invention describes novel lercanidipine (I) crude forms (A) and (B), novel I-HCl cryst. forms I and II obtained from crude forms, pharmaceutical, antihypertensive compns. contg. as active agent at least one of the I-HCl cryst. forms I and II and methods of use.In this study，132866-11-6 is also used. I-HCl was prepd. and the cryst. forms obtained by crystn. from various solvents. The bioavailability of the various forms was also detd. ..
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