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134-90-7

Basic Information
CAS No.: 134-90-7
Name: [S-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
Article Data: 47
Molecular Structure:
Molecular Structure of 134-90-7 ([S-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide)
Formula: C11H12 Cl2 N2 O5
Molecular Weight: 323.133
Synonyms: Acetamide,2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[S-(R*,R*)]-; Acetamide, 2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]-, L-threo- (6CI); Acetamide,2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]-,L-threo-(+)- (8CI); (+)-Chloramphenicol; (1S,2S)-2-(2,2-Dichloroacetamido)-1-(4-nitrophenyl)-1,3-propanediol;Dextramycin; Dextromycetin; L-(+)-threo-Chloramphenicol;L-threo-(1S,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol;L-threo-Chloramphenicol; L-threo-Chloroamphenicol;L-threo-N-Dichloracetyl-1-p-nitrophenyl-2-amino-1,3-propanediol;L-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
Density: 1.547g/cm3
Melting Point: 150-151 °C
Boiling Point: 644.9°C at 760 mmHg
Flash Point: 343.8°C
Safety: Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other chloramphenicol entries.
PSA: 115.38000
LogP: 1.82310
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Chemistry

Product Name: Dextramycine
CAS Registry Number: 134-90-7
IUPAC Name: 2,2-dichloro-N-[(1S,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Molecular Weight: 323.12938 [g/mol]
Molecular Formula: C11H12Cl2N2O5
XLogP3: 1.1
H-Bond Donor: 3
H-Bond Acceptor: 5 
EINECS: 205-161-2
Surface Tension: 66.1 dyne/cm
Density: 1.547 g/cm3
Flash Point: 343.8 °C
Enthalpy of Vaporization: 99.98 kJ/mol
Boiling Point: 644.9 °C at 760 mmHg
Vapour Pressure: 1.63E-17 mmHg at 25°C
Following is the molecular structure of Dextramycine (CAS NO.134-90-7) is:

Toxicity Data With Reference

1.    

mmo-sat 600 µmol/L

    BBRCA9    Biochemical and Biophysical Research Communications. 78 (1977),151.
2.    

dnd-sat 5 mmol/L

    BBRCA9    Biochemical and Biophysical Research Communications. 78 (1977),151.
3.    

dnd-esc 500 µmol/L

    BBRCA9    Biochemical and Biophysical Research Communications. 78 (1977),151.

Consensus Reports

EPA Genetic Toxicology Program.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other chloramphenicol entries.

Specification

 Dextramycine , its cas register number is 134-90-7. It also can be called (+)-Chloramphenicol ; Dextramycin ; Dextromycetin ; EINECS 205-161-2 ; L-(+)-Threo-chloramphenicol ; L-Chloramphenicol  ; L-threo-(1S,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol ; L-threo-Chloramphenicol ; L-threo-Chloroamphenicol ; L-threo-N-Dichloracetyl-1-p-nitrophenyl-2-amino-1,3-propanediol ; threo-Chloramphenicol, l- ; (S-(R*,R*))-2,2-Dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)acetamide ; Acetamide, 2,2-dichloro-N-((1S,2S)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)- ; Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (S-(R*,R*))- ; Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-, L-threo-(+)- .