CAS No.134419-57-1,2-Azetidinecarboxylicacid, methyl ester Suppliers

Products Categories

Pharmaceutical (20)
Organic Chemicals (6)
Others (4)

Basic Information

Molecular Structure:
CAS No.:	134419-57-1
Name:	2-Azetidinecarboxylicacid, methyl ester
Article Data:	5

Formula:	C₅H₉NO₂
Molecular Weight:	115.132
Synonyms:	Methyl2-azetidinecarboxylate;
Density:	1.1 g/cm³
Boiling Point:	144.666 °C at 760 mmHg
Flash Point:	41.293 °C
PSA:	38.33000
LogP:	-0.14990

Synthetic route

: 67-56-1
methanol

: 2517-04-6
Azetidine-2-carboxylic acid

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

Conditions

Conditions	Yield
With thionyl chloride for 24h; Ambient temperature;
With thionyl chloride for 1h; Heating;

: 18085-37-5
methyl 1-benzyl-2-azetidinecarboxylate

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

Conditions

Conditions	Yield
With ammonium formate; palladium on activated charcoal In methanol for 0.75h; Heating;

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 501-53-1
benzyl chloroformate

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: (2S)-methyl-1-(benzyloxycarbonyl)azetidine-2-carboxylate

Conditions

Conditions	Yield
In dichloromethane	80%

...Expand

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 13551-90-1
2-nitro-1-(2-oxiranylmethyl)-1H-imidazole

: 134419-52-6
1-[2-Hydroxy-3-(2-nitro-imidazol-1-yl)-propyl]-azetidine-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
In methanol for 3h; Heating;	16%

: 3282-30-2
pivaloyl chloride

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 145642-59-7
Methyl N-Pivaloylazetidine-2-carboxylate

Conditions

Conditions	Yield
With pyridine In dichloromethane for 20h; Ambient temperature; Yield given;

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 7154-66-7
2-bromobenzoic acid chloride

: 182343-74-4
1-(2-Bromo-benzoyl)-azetidine-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
With triethylamine In dichloromethane Ambient temperature; Yield given;

: 59813-11-5
2-bromoethyl diazomethyl ketone

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 860775-87-7
methyl 1-(3'-oxo-4'-diazo)butylaziridine-2-carboxylate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 16h;	0.264 g

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 25471-73-2, 113890-49-6, 113890-50-9
(1S,7aR)-7-Oxo-hexahydro-pyrrolizine-1-carboxylic acid methyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 0.264 g / iPr2NEt / acetonitrile / 16 h / 20 °C 2: Cu(acac)2 / toluene / 85 °C View Scheme

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 25471-73-2, 113890-49-6, 113890-50-9
(5α)-1-aza-4α-carbomethoxy-6-oxobicyclo<3.3.0>octane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 0.264 g / iPr2NEt / acetonitrile / 16 h / 20 °C 2: Cu(acac)2 / toluene / 85 °C View Scheme

: 134419-57-1
(2S)-methyl azetidine-2-carboxylate

: 2-Allyl-1-benzoyl-azetidine-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: Et3N / CH2Cl2 / Ambient temperature 2: 51 percent / (TMS)2NLi / tetrahydrofuran; hexane / 1.) -78 deg C, 15 min, 2.) r.t., 5 h 3: 63 percent / Bu3SnH, AIBN / toluene / 2 h / Heating View Scheme

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:28 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 134419-57-1

Specification

The 2-Azetidinecarboxylicacid, methyl ester is an organic compound with the formula C₅H₉NO₂. The systematic name of this chemical is methyl azetidine-2-carboxylate. With the CAS registry number 134419-57-1, it is also named as Azetidine-2-carboxylic acid methyl ester. The product's category is Pharmacetical.

Physical properties about 2-Azetidinecarboxylicacid, methyl ester are: (1)ACD/LogP: -0.66; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1; (5)ACD/KOC (pH 7.4): 1; (6)#H bond acceptors: 3; (7)#H bond donors: 1; (8)#Freely Rotating Bonds: 2; (9)Polar Surface Area: 38.33 Å²; (10)Index of Refraction: 1.45; (11)Molar Refractivity: 28.134 cm³; (12)Molar Volume: 104.623 cm³; (13)Polarizability: 11.153×10^-24cm³; (14)Surface Tension: 33.84 dyne/cm; (15)Density: 1.1 g/cm³; (16)Flash Point: 41.293 °C; (17)Enthalpy of Vaporization: 38.174 kJ/mol; (18)Boiling Point: 144.666 °C at 760 mmHg; (19)Vapour Pressure: 5.038 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: COC(=O)C1CCN1
(2)InChI: InChI=1/C5H9NO2/c1-8-5(7)4-2-3-6-4/h4,6H,2-3H2,1H3
(3)InChIKey: CHNOQXRIMCFHKZ-UHFFFAOYAW
(4)Std. InChI: InChI=1S/C5H9NO2/c1-8-5(7)4-2-3-6-4/h4,6H,2-3H2,1H3
(5)Std. InChIKey: CHNOQXRIMCFHKZ-UHFFFAOYSA-N