Detail of "134759-22-1"

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Label-free high throughput biomolecular screening system and method

All Rights Reserved. Label-free high throughput biomolecular screening system and method. Caracci, Stephen J.; Eckelt, Volker H. O.; Frutos, Anthony G.; Krol, Mark F.; Moore, Thomas C.; Pastel, David A.; Shedd, Gordon M. (USA ). U.S. Pat.There are some reagents with their cas registry numbers 9013-20-1 and 134759-22-1 are used in this study. Appl. Publ. US 2007020689 A1 25 Jan 2007,29pp. (English). (United States of America). CODEN: USXXCO. INCL: 435007100; 435287200; 702019000. APPLICATION: US 2006-489173 19 Jul 2006. PRIORITY: US 2005-701445P 20 Jul 2005. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacology) A screening system and method are described herein which provide a unique and practical soln. for enabling label-free high throughput screening (HTS) to aid in the discovery of new drugs. In one embodiment, the screening system enables direct binding assays to be performed in which a biomol. interaction of a chem. compd. (drug candidate) with a biomol. (therapeutic target) can be detected using assay vols. and concns. that are compatible with the current practices of HTS in the pharmaceutical industry. The screening system also enables the detection of bio-chem. interactions that occur in the wells of a microplate which incorporates biosensors and surface chem. to immobilize the therapeutic target at the surface of the biosensors. The screening system also includes fluid handling and plate handling devices to help perform automated HTS assays. .