Reference

Highly Enantioselective Construction of a Chiral Spirocyclic Structure by the [2+2+2] Cycloaddition of Diynes and exo-Methylene Cyclic Compounds

Tsuchikama, Kyoji; Kuwata, Yusuke; Shibata, Takanori (Department of Chemistry, School of Science and Engineering, Waseda University, Tokyo 169-8555, Japan). Journal of the American Chemical Society, 128(42), 13686-13687 (English) 2006 American Chemical Society. CODEN: JACSAT. ISSN: 0002-7863. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 25 The enantioselective [2+2+2] cycloaddn.There are some reagents like 135139-00-3 is used in this study. of 1,6-diynes with a-methylene lactones and cyclic ketones gave various chiral spirocyclic compds. The reaction proceeded with high enantioselectivity when the rhodium-xylylBINAP complex was used as a chiral catalyst. Not only exo-methylene cyclic compds. 135139-00-3 is the cas registry number of certain chemical which is used as reagents here. but also exo-methylene acyclic compds. could be used as coupling partners for diynes. The present protocol provides access to a new chiral library possessing a quaternary carbon center, including a spirocyclic system. ..

Enantioselective Synthesis of Planar-Chiral Metacyclophanes through Rhodium-Catalyzed Alkyne Cyclotrimerization

All Rights Reserved. Enantioselective Synthesis of Planar-Chiral Metacyclophanes through Rhodium-Catalyzed Alkyne Cyclotrimerization. Tanaka, Ken; Sagae, Hiromi; Toyoda, Kazuki; Noguchi, Keiichi; Hirano, Masao (Department of Applied Chemistry Graduate School of Engineering and Instrumentation Analysis Center, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan). Journal of the American Chemical Society, 129(6), 1522-1523 (English) 2007 American Chemical Society. CODEN: JACSAT. ISSN: 0002-7863. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) The first catalytic enantioselective synthesis of planar-chiral metacyclophanes via cationic rhodium(I)/(R)-H8-BINAP complex-catalyzed alkyne cyclotrimerization is described. 135139-00-3 is also in the experiment. This reaction represents a versatile new method for the prepn.There are some reagents like 135139-00-3 is used in this study. of planar-chiral [7]-[10]metacyclophanes. ..