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| CAS No.: | 13726-52-8 | ||||
|---|---|---|---|---|---|
| Name: | N-(4-AMINOBENZOYL)-L-GLUTAMIC ACID DIETHYL ESTER | ||||
| Article Data: | 15 | ||||
| Molecular Structure: | |||||
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|
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| Formula: | C16H22 N2 O5 | ||||
| Molecular Weight: | 322.361 | ||||
| Synonyms: | Glutamicacid, N-(p-aminobenzoyl)-, diethyl ester (6CI,7CI); Glutamic acid,N-(p-aminobenzoyl)-, diethyl ester, L- (8CI); L-Glutamic acid,N-(4-aminobenzoyl)-, diethyl ester (9CI); 4-Aminobenzoyl-L-glutamic acid,diethyl ester; Diethyl p-aminobenzoyl-L-glutamate;N-(4-Aminobenzoyl)-L-glutamic acid diethyl ester; NSC 82885 | ||||
| Density: | 1.187g/cm3 | ||||
| Melting Point: |
139-142 °C(lit.) |
||||
| Boiling Point: | 522°Cat760mmHg | ||||
| Flash Point: | 269.5°C | ||||
| Appearance: | white to off-white powder | ||||
| Safety: |
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| PSA: | 107.72000 | ||||
| LogP: | 2.24570 | ||||
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- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 7148-24-5
diethyl (4-nitrobenzoyl)-L-glutamate
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| With potassium fluoride; polymethylhydrosiloxane; palladium diacetate In tetrahydrofuran at 20℃; for 0.5h; | 100% |
| With sodium tetrahydroborate In tetrahydrofuran; water at 20℃; for 6h; Inert atmosphere; Green chemistry; chemoselective reaction; | 86% |
| With sodium tetrahydroborate; iron; water at 20℃; for 6h; | 86% |
| Hydrogenation; | |
| With ethanol; palladium Hydrogenation; |
- 76807-59-5
Diethyl 8-Deazaaminopterin
A
- 1955-57-3
6-methylpyrido<3,2-d>pyrimidine-2,4-diamine
B
- 939436-99-4
diethyl N-[4-[[2-(2,4-diamino-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamate
C
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| With platinum(IV) oxide; hydrogen; acetic acid In ethanol at 40℃; under 2.25023 Torr; for 48h; | A 5% B 67.7% C 8% |
- 76807-65-3
Diethyl 8-Deazafolic Acid
A
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
B
- 78711-33-8
2-amino-5,6,7,8-tetrahydro-6-methylpyrido<3,2-d>pyrimidin-4(3H)-one
C
- 82855-85-4
diethyl 5,6,7,8-tetrahydro-8-deazafolate
| Conditions | Yield |
|---|---|
| With hydrogenchloride; hydrogen; platinum(IV) oxide In ethanol under 2172.02 Torr; for 3h; | A n/a B n/a C 60% |
- 496961-74-1
N-[4-(toluene-4-sulfonylamino)-benzoyl]-L-glutamic acid diethyl ester
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| With hydrogen bromide; acetic acid; phenol | |
| With hydrogen bromide; acetic acid; phenol |
- 4271-30-1
N-(4-aminobenzoyl)-L-glutamic acid
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| With hydrogenchloride; ethanol |
- 56-86-0
L-glutamic acid
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: aq. NaOH solution 3: palladium; ethanol / Hydrogenation View Scheme |
- 6758-40-3
p-Nitrobenzoyl-L-(+)-glutamic acid
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 2: palladium; ethanol / Hydrogenation View Scheme |
- 122-04-3
4-nitro-benzoyl chloride
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: benzene 2: palladium; ethanol / Hydrogenation View Scheme |
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
- 100-52-7
benzaldehyde
- 70280-70-5
diethyl N--L-glutamate
| Conditions | Yield |
|---|---|
| With bromocresol green; sodium cyanoborohydride; acetic acid In ethanol for 48h; Ambient temperature; | 94% |
| With sodium cyanoborohydride |
- 24424-99-5
di-tert-butyl dicarbonate
- 13726-52-8
diethyl N-(p-aminobenzoyl)-L-glutamate
| Conditions | Yield |
|---|---|
| With zinc(II) perchlorate In dichloromethane at 20℃; for 164h; | 94% |
- Total:27 Page 1 of 1 1
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