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Basic Information
| CAS No.: | 13764-49-3 |
|---|---|
| Name: | ETORPHINE HYDROCHLORIDE |
| Molecular Structure: | |
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| Formula: | C25H33NO4•ClH |
| Molecular Weight: | 448.05 |
| Density: | 1.3g/cm3 |
| Boiling Point: | 549.7°Cat760mmHg |
| Flash Point: | 286.2°C |
| Safety: | Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. |
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Chemistry
Etorphine hydrochloride(13764-49-3)'s molecular formula is C25H33NO4ClH.
Etorphine Hydrochloride(13764-49-3) is (6R,7R,14R)-7,8-dihydro-7-[(1R)-1-hydroxy-1-methylbutyl]-6-O-methyl-6,14-ethenomorphine hydrochloride. It contains not less than 98.0% and not more than of 101.0% of C25H33NO4ClH, calculated with reference to the dried substance.
Etorphine Hydrochloride(13764-49-3) is a white or almost white, microcrystalline powder.
It is sparingly soluble in water and in ethanol (96%) and very slightly soluble in chloroform and practically insoluble in ether.
The molecular structure of Etorphine Hydrochloride(13764-49-3):
Etorphine Hydrochloride(13764-49-3) is (6R,7R,14R)-7,8-dihydro-7-[(1R)-1-hydroxy-1-methylbutyl]-6-O-methyl-6,14-ethenomorphine hydrochloride. It contains not less than 98.0% and not more than of 101.0% of C25H33NO4ClH, calculated with reference to the dried substance.
Etorphine Hydrochloride(13764-49-3) is a white or almost white, microcrystalline powder.
It is sparingly soluble in water and in ethanol (96%) and very slightly soluble in chloroform and practically insoluble in ether.
The molecular structure of Etorphine Hydrochloride(13764-49-3):
Toxicity Data With Reference
| 1. | orl-rat LD50:72 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 30 (1967),11. | ||
| 2. | scu-rat LD50:53 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 30 (1967),11. | ||
| 3. | ivn-rat LD50:5300 µg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 30 (1967),11. | ||
| 4. | orl-mus LD50:1856 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 30 (1967),11. | ||
| 5. | scu-mus LD50:425 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 30 (1967),11. | ||
| 6. | ivn-mus LD50:80 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 30 (1967),11. |
Safety Profile
Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Specification
CAUTION
Etorphine Hydrochloride(13764-49-3) is extremely potent and extraordinary care should be taken in any procedure in which it is used. Any spillage on the skin should be washed off at once. In the case of accidental injection or absorption through broken skin or mucous membrane, a reversing agent should be injected immediately.