Detail of "138331-02-9"

Reference

Purified amphiphilic peptide compositions and uses thereof

Purified amphiphilic peptide compositions and uses thereof. (3D Matrix, Inc., USA). PCT Int. Appl. WO 2006014570 A2 9 Feb 2006, 47 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IS, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). 68-04-2 which is the cas registry number is also used here. CODEN: PIXXD2. 138331-02-9 is also in the experiment. CLASS: ICM: C07K. APPLICATION: WO 2005-US24198 6 Jul 2005. PRIORITY: US 2004-2004/PV58591U 6 Jul 2004; US 2005-2005/176781 6 Jul 2005. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) A plurality of amphiphilic peptide chains having alternating hydrophilic and hydrophobic amino acids, wherein the peptide contains at least 8 amino acids, are complementary and structurally compatible, and self-assemble into a beta-sheet macroscopic scaffold wherein peptide at least about 75% of the chains have the same sequence. Thus, treatment with 3% peptide chain soln. assembled in NaCl resulted in continuous thicker bone, while treatment with the same soln. assembled in media resulted in discontinuous bone and the formation of fibrous tissue. ..