Detail of "13836-37-8"

CAS Number:
13836-37-8
Name:
L-Ornithine,N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-
Superlist Name:
N-Boc-N'-tosyl-L-arginine
Molecular Structure:
Formula:
C₁₈H₂₈N₄O₆S
Molecular Weight:
428.50
Deleted CAS:
111155-39-6|128625-53-6|129009-89-8|158328-87-1|54784-62-2|62526-85-6|62720-22-3
Synonyms:
Ornithine,N2-carboxy-N5-[(p-tolylsulfonyl)amidino]-, N2-tert-butyl ester, L- (7CI,8CI);N2-tert-Butoxycarbonyl-NG-tosyl-L-arginine;NSC 164058;Boc-Arg(Tos)-OH;
EINECS:
237-549-2
Density:
1.31 g/cm³
Melting Point:
~90 °C (dec.)
Safety:
22-24/25 Details

Display：

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Des-proline-des-glycine vasopressin antagonists: Des-proline-des-glycine vasopressin antagonists. 11000-17-2 is also in the experiment. Ali, Fadia E.; Huffman, William F. (Smithkline Beckman Corp., USA). U.S. US 4481194 A 6 Nov 1984, 7 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K037-00; C07C103-52. NCL: 424177000. APPLICATION: US 84-586934 7 Mar 1984. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 2, 34 Cyclic heptapeptides, I where P = Phe or Phe(4'-C1-4 alkyl), X = D-Phe, D-Val, L-Tyr, etc., Y = Val, Ile, etc., Z = D-Ary, L-Arg, D-Lys, or L-Lys, A = OH, NH2, or NH-C14 alkyl, and n = 0-2, were prepd. as vasopressin [11000-17-2] antagonists. Pharmaceutical compns. contg. the compds. were described. E.g., BOC-Arg(tosyl) [13836-37-8] was reacted with resin-bound benzhydrylamine and the resultant resin-bound BOC-Arg(tosyl)-benzhydrylamine was coupled sequentially with protected amino acids in a peptide synthesizer to give resin-bound b-mercapto-b,b-cyclopentamethylenepropionyl-4-methylbenzyl-D-Tyr(Et )-Phe-Val-Asn-Cys(4-methylbenzyl)-Arg(tosyl)-benzhydrylamine (II). II was treated with HF to give b-mercapto-b,b-cyclopentamethylenepropyl-D-Tyr(Et)-Phe-Val-Asn-C ys-Arg(NH2) (III) [94497-37-7]. Parenteral dosage units contained 0.5 mg III in 1 mL of an aq. soln. of 20 mg mannitol lyophilized in a ampul for reconstitution. .

Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, and their compositions: Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, and their compositions. Nestor, John J.; Vickery, Brian H. (Syntex (U.S.A.), Inc., USA). Eur. Pat. Appl. EP 97031 A2 28 Dec 1983, 77 pp. DESIGNATED STATES: R: AT, BE, CH, DE, FR, GB, IT, LI, LU, NL, SE. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: IC: C07C103-52; A61K037-02. APPLICATION: EP 83-303343 9 Jun 1983. PRIORITY: US 82-387101 10 Jun 1982; US 82-451671 21 Dec 1982; US 83-472692 7 Mar 1983; US 83-495226 20 May 1983. DOCUMENT TYPE: Patent CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 2 Nona- and decapeptide analogs of LH-RH, which contained the -Arg-Pro- fragment in the 8-9 position, were prepd. by the solid-phase method. Some amino acid analogs were also prepd. and incorporated in the peptides. Thus decapeptide amide I had ovulation-inhibiting ED50 of 0. 13836-37-8 and 89662-16-8 which are cas registry numbers of substances are two of reagents here.67 mg in std. test (A. Corbin, C. W. Beattie, 1975). .