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| CAS No.: | 14047-28-0 |
|---|---|
| Name: | (R)-(+)-9-(2-Hydroxypropyl)adenine |
| Article Data: | 37 |
| Molecular Structure: | |
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|
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| Formula: | C8H11N5O |
| Molecular Weight: | 193.208 |
| Synonyms: | 9H-Purine-9-ethanol,6-amino-a-methyl-, (R)-;9H-Purine-9-ethanol, 6-amino-a-methyl-, D- (8CI);(R)-9-(2-Hydroxypropyl)adenine;9-[(2R)-2-Hydroxypropyl]adenine;D-(-)-9-(2-Hydroxypropyl)adenine; |
| EINECS: | 604-188-0 |
| Density: | 1.57 g/cm3 |
| Melting Point: | 193 °C |
| Boiling Point: | 457.7 °C at 760 mmHg |
| Flash Point: | 230.6 °C |
| PSA: | 89.85000 |
| LogP: | 0.37050 |
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- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With sodium hydroxide In water at 93℃; for 2h; Temperature; | 97.7% |
- 180587-74-0
(R)-1-(6-chloro-9H-purin-9-yl) propan-2-ol
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With ammonium hydroxide In 1,4-dioxane at 100 - 110℃; Sealed tube; Large scale; | 96.3% |
| With ammonia at 65℃; | 91% |
| With monomethanolamine In water at 0 - 60℃; for 48h; | 76% |
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With D-tartaric acid; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0℃; Concentration; Reagent/catalyst; Temperature; | 95.4% |
- 4121-40-8
9-propenyladenine
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine) In dichloromethane at 15℃; for 5h; Temperature; Concentration; | 94.7% |
- 852954-49-5
(R)-5-amino-1-(2-hydroxypropyl)-1H-imidazole-4-carbonitrile
- 3473-63-0
formamidine acetic acid
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With barium hydroxide monohydrate In N,N-dimethyl-formamide for 16h; Solvent; Concentration; Heating; | 93% |
| Conditions | Yield |
|---|---|
| With sodium hydroxide In N,N-dimethyl-formamide at 145℃; Temperature; Large scale; | 89.5% |
| With sodium hydroxide In N,N-dimethyl-formamide at 90 - 140℃; for 12h; Inert atmosphere; | 87% |
| With sodium hydroxide In N,N-dimethyl-formamide at 130 - 140℃; for 12h; Inert atmosphere; | 87% |
- 160616-02-4
(R)-9-<2-(2-tetrahydropyranyloxy)propyl>adenine
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With sulfuric acid Ambient temperature; | 85% |
- 73-24-5
7H-purin-6-ylamine
- 16606-55-6
(R)-1,2-propylene carbonate
B
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With sodium hydroxide In N,N-dimethyl-formamide for 8h; Reflux; | A 8% B 80% |
| Conditions | Yield |
|---|---|
| With sodium carbonate In N,N-dimethyl-formamide at 95℃; for 6h; Reagent/catalyst; Temperature; | 69% |
- 105970-02-3
1-(6-amino-9H-purin-9-yl)propan-2-one
- 14047-28-0
(R)-9-(2-hydroxypropyl)adenine
| Conditions | Yield |
|---|---|
| With dichloro(benzene)ruthenium(II) dimer; sodium formate; (R)-α,α-diphenylprolinol In acetonitrile at 20 - 30℃; for 48h; enantioselective reaction; | 64% |
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Chemistry
Product Name: (R)-(+)-9-(2-Hydroxypropyl)adenine (CAS NO.14047-28-0)
Molecular Formula: C8H11N5O
Molecular Weight: 193.21g/mol
Mol File: 14047-28-0.mol
Melting Point: 193 °C
Boiling point: 457.7 °C at 760 mmHg
Flash Point: 230.6 °C
Density: 1.57 g/cm3
Surface Tension: 68.5 dyne/cm
Enthalpy of Vaporization: 75.64 kJ/mol
Vapour Pressure: 3.6E-09 mmHg at 25°C
Product Categories: Chiral Reagents; Bases & Related Reagents; Nucleotides
Specification
(R)-(+)-9-(2-Hydroxypropyl)adenine , its CAS NO. is 14047-28-0, the synonyms are R-9-(2-hydroxypropyl) adenine, 9-HPA ; (R)-(+)-9-(2-Hydroxypropyl)adenine ; 6-Amino-alpha-methyl-9H-purine-9-ethanol ; D-(-)-9-(2-Hydroxypropyl)adenine .