Detail of "1406-11-7"

Reference

Anaerobic infection in the neutropenic host: anti-endotoxin effect of polymyxin

Anaerobic infection in the neutropenic host: anti-endotoxin effect of polymyxin. Bannatyne, Robert M.; Cheung, Rose (Dep. Bacteriol., Hosp. Sick Child., Toronto, ON M5G 1X8, Can.). Anticancer Res., 4(3), 169-70 (English) 1984. CODEN: ANTRD4. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The neutropenic mouse model of endotoxin-assocd. anaerobic sepsis was used to evaluate the anti-endotoxic effect of polymyxin [1406-11-7]. Administered as 2 spaced doses after lethal challenge with Bacteroides fragilis, polymyxin produced a statistically significant protective effect.

Veterinary compositions for treatment of mammary infections of cattle and goats

Veterinary compositions for treatment of mammary infections of cattle and goats. Lacombe, Jean Francois Paul Louis (Fr. ). Eur. Pat. Appl. EP 97580 A1 4 Jan 1984,18 pp. DESIGNATED STATES: R: AT, BE, CH, DE, FR, GB, IT, LI, LU, NL, SE.Chemicals with cas numbers 1406-11-7 and 114-07-8 also play role. (French). (European Patent Organization). CODEN: EPXXDW. CLASS: IC: A61K037-54. ICI: A61K037-54, A61K037-02, A61K031-71. APPLICATION: EP 83-401232 15 Jun 1983. PRIORITY: FR 82-10927 16 Jun 1982. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Veterinary compns. with antimicrobial properties consist of a mixt. of 2 antibiotics and an enzyme and are used for the treatment of mammary infections. Thus, a compn. contained a mixt. of erythromycin thiocyanate [7704-67-8] 200 mg (corresponding to the base), and lysozyme-HCl [9066-59-5] 30 mg, polymyxin B sulfate [1405-20-5] 50,000 IV, and pH 6.8 buffer q.s.p. to 100 mL. The compn. may be used for the treatment of infections from both gram pos. and gram neg. bacteria. The effectiveness of the compn. was demonstrated in the treatment of infection in cows. The animals tolerated the compn. well. .