Detail of "14365-44-7"

Supplier:Shanghai Howson Biotech., Ltd. [ China (Mainland)]

630 Integral
630

Tel:86-21-62277841

Address:B-7C,1068, Xikang Road, Shanghai, China

Supplier:AXXORA, LLC [ Switzerland]

600 Integral
600

Tel:+41 (0) 61 926 8989

Address:Industriestrasse 17

Supplier:BIOLOG [ Germany]

610 Integral
610

Tel:+49 421 591355

Address:P.O. Box 107125 D-28071 Bremen

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Nucleoside 5'-monophosphate analogues: Nucleoside 5'-monophosphate analogues. Synthesis of 5'-sulfamino-5'-deoxynucleosides. Mungall, William S.; Lemmen, L. James; Lemmen, Kathleen L.; Dethmers, Judy Kaiser; Norling, Laura L. (Dep. Chem., Hope Coll., Holland, Mich., USA). J. Med. Chem., 21(7), 704-6 (English) 1978. CODEN: JMCMAR. ISSN: 0022-2623. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 3 5'-Sulfamino-5'-deoxyadenosine Na salt (I) [66825-41-0] and 5'-sulfamino-5'-deoxythymidine Na salt (II) [66801-17-0] were synthesized by reaction of Me3N×SO3 [3162-58-1] with 5'-amino-5'-deoxyadenosine [14365-44-7] and 5'-amino-5'-deoxythymidine [25152-20-9], resp. I and II were stable in acidic or basic aq. soln. Neither I and II inhibited the growth of Escherichia coli or L1210 cells at <10-4M. At 10-4M, II inhibited the replication of herpes simplex virus (type 1) by 70% with no effect on host cell growth.