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Detail of "143824-78-6"

  • CAS Number:
  • 143824-78-6
  • Name:
  • Fmoc-Trp(Boc)-OH

  • Molecular Structure:
  • Formula:
  • C31H30N2O6
  • Molecular Weight:
  • 526.59
  • Synonyms:
  • N-α-Fmoc-N-in-Boc-L-tryptophan;Fmoc-L-Trp(Boc)-OH;
  • Density:
  • 1.289 g/cm3
  • Melting Point:
  • 86 - 90 °C
  • Appearance:
  • White to off-white crystalline powder
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 36/37/38
  • Safety:
  • 22-24/25-36/37/39-27-26 Details
  • particular:
  • particular

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OHCompetitive Product

Fmoc-Trp(Boc)

Supplier:Chengdu Baishixing Science and Technology Industry Co., Ltd. [ China (Mainland)]

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OHCompetitive Product

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Assay:99%  Appearance:White Powder  Package:bags

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Fmoc-Trp(Boc)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Assay:≥96.0%(HPLC)  Appearance:White to off...

Solubility:1mmol in 2ml DMF clear solution Specific Rotation([α]D20):-19±2°(C=1 in DMF)

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Fmoc-Trp(Boc)-OH.99%. We're the professional research & develop company, not a trader.We can give the most competitive price.

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Assay:98%

Supplier:GL Biochem(Shanghai) Ltd. [ China (Mainland)]

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Assay:99%  Appearance:White to off...  Package:500g/bottle ...Storage:store at a c...  Transportation:by sea  Application:used in pept...

1.used in peptides and pharmaceuticals 2.Good quality & low price 3.98.5%min by HPLC 4.Fast delivered used in peptides and pharmaceuticals Name: Fmoc-Trp(Boc)-OH Category: Fmoc-Amino Acids Product Name Fmoc-L-Trp(Boc)-OH,peptide CAS No.

Min. Order:1Kilogram

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Item Standard Appearance White to off-white powder Purity (HPLC) ≥98.50% Purity(TLC) ≥98.5% Loss on Drying ≤0.50% Water Content(KF) ≤1.00% Specific Rotation [20/D] -19.5±2.0 Degree(c=1 in DMF) Solubility 5 mmole in 10 ml DMF clearly soluble

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

more information,pls contact with us!

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

≥99%

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

Fmoc-Trp(Boc)-OH HPLC>>98.0%

Supplier:Sichuan Goldentree Bio-pharmaceutical Co.,Ltd [ China (Mainland)]

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

97%

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

FMOC-TRP(BOC)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

more information,pls contact with us!

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FMOC-TRP(BOC)-OH

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FMOC-TRP(BOC)-OH

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CAS No.143824-78-6 Fmoc-Trp(Boc)-OH

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Reference

In Silico and NMR Identification of Inhibitors of the IGF-I and IGF-Binding Protein-5 Interaction
In Silico and NMR Identification of Inhibitors of the IGF-I and IGF-Binding Protein-5 Interaction. Kamionka, Mariusz; Rehm, Till; Beisel, Hans-Georg; Lang, Kurt; Engh, Richard A.In this study, 35661-40-6 and 143824-78-6 are also used.; Holak, Tad A. (Max Planck Institute for Biochemistry, Martinsried D-82152, Germany). Journal of Medicinal Chemistry, 45(26), 5655-5660 (English) 2002 American Chemical Society. CODEN: JMCMAR. ISSN: 0022-2623. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Recently we have detd. the crystal structure of the insulin-like growth factor-I (IGF-I) in complex with the N-terminal domain of the IGF-binding protein-5 (IGFBP-5). Here we report results of computer screening for potential inhibitors of this interaction using the crystal coordinates. From the compds. suggested by in silico screens, successful binders were identified by NMR spectroscopic methods. NMR was also used to map their binding sites and calc. their binding affinities. Small mol. wt. compds. (FMOC derivs.) bind to the IGF-I binding site on the IGFBP-5 with micromolar affinities and thus serve as potential starting compds. for the design of more potent inhibitors and therapeutic agents for diseases that are assocd. with abnormal IGF-I regulation. .
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