Reference

Wittig reaction

Wittig reaction. III. Wittig reaction using polyethylene glycol as phase-transfer catalyst. Lu, Zekai; Peng, Hong; Gu, Lianquan; Huang, Wenfang (Inst.Chemical with cas number 1449-46-3 also plays role. Agrochem., Cent. China Norm. Univ., Wuchang, Peop. Rep. China). Huazhong Shifan Daxue Xuebao, Ziran Kexueban, (4), 44-7 (Chinese) 1985. CODEN: HDZKEL. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) The Wittig reaction of Ph3P+CH2RX- (R = Ph, CO2Me, Me; X = Br, iodo) with R1CHO (R1 = Ph, p-MeOC6H4) using polyethylene glycol as phase-transfer catalyst was studied. The E/Z ratio of products R1CH:CHR was ~1-1.3 in 70-95% yields. The results were compared to those obtained in reactions without a catalyst or using crown ether as catalyst. The effects of solvent, reaction temp., and reaction time on the yields and E/Z ratio of products were also studied. .

An approach towards chiral 5-hydroxyalkylbutan-4-olides: total synthesis of (-)-muricatacin and related natural products

An approach towards chiral 5-hydroxyalkylbutan-4-olides: total synthesis of (-)-muricatacin and related natural products. Chandrasekhar, M.; Chandra, Kusum L.; Singh, Vinod K. (Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India). ARKIVOC (Gainesville, FL, United States) [online computer file], (7), 34-45 (English) 2002 Arkat USA Inc. URL: http://www.arkat-usa.org/ark/journal/2002/SKessar/SK-387E/387E.htm. CODEN: AGFUAR. 486999-33-1 and 445396-65-6 are also in the experiment. DOCUMENT TYPE: Journal; (online computer file) CA Section: 26 (Biomolecules and Their Synthetic Analogs) Section cross-reference(s): 33 A general approach towards synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol has been described. The approach has been used successfully for total synthesis of (-)-muricatacin, an anti-tumor natural product. Other related natural and unnatural compds.In this experiment, several chemicals are used like 1449-46-3 were also synthesized. ..