CAS No.145-42-6,Sodium taurocholate Suppliers

Products Categories

Pharmaceutical (121)
Organic Chemicals (24)
Others (17)
Plant Extract (8)
Reagent (7)
Materials (5)
Basic Inorganic Chemicals (1)
Catalyst and Auxiliary (1)

Basic Information

Molecular Structure:
CAS No.:	145-42-6
Name:	Sodium taurocholate
Article Data:	3

Formula:	C₂₆H₄₄NaO₇S
Molecular Weight:	537.694
Synonyms:	Taurine,N-choloyl-, monosodium salt (8CI);Monosodium taurocholate;Taurocholate sodium;Taurocholicacid monosodium salt;Taurocholic acid sodium salt;Monosodium 2-(((3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)ethanesulfonate;Taurine, N-choloyl-, monosodium salt;
EINECS:	205-653-7
Density:	1.177 g/cm3(Temp: 22.5 °C)
Melting Point:	230 °C
Flash Point:	9℃
Solubility:	0.5 M in water at 20 °C
Appearance:	White powder.
Risk Codes:	36/37/38
Safety:	26-36/37/39-24/25
PSA:	155.37000
LogP:	3.49720

Synthetic route

: 107-35-7
Tau

: 81-25-4
cholic acid

: 145-42-6
sodium taurocholate

Conditions

Conditions	Yield
Stage #1: Tau; cholic acid With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine In N,N-dimethyl-formamide at 90℃; for 2h; Stage #2: With sodium hydroxide In methanol at 20℃; for 1h;	95%
With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; sodium hydroxide In water; dimethyl sulfoxide; acetonitrile; tert-butyl alcohol at 20 - 80℃;	88%

: 17050-09-8
2-[carbamimidoyl(methyl)amino]acetic acid hydrochloride

: 145-42-6
sodium taurocholate

: amino((carboxymethyl)(methyl)amino)methaniminium 2-((R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate

Conditions

Conditions	Yield
In ethanol at 50℃; for 4h;	97%

: 15366-32-2
ethyl 2-(3-methylguanidino)acetate hydrochloride

: 145-42-6
sodium taurocholate

: amino((2-ethoxy-2-oxoethyl)(methyl)amino)methaniminium 2-((R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate

Conditions

Conditions	Yield
In ethanol at 50℃; for 4h;	95%

: 145-42-6
sodium taurocholate

: 82660-96-6
N-nitrosotaurochoic acid

Conditions

Conditions	Yield
With sodium acetate; nitrosylchloride In acetic acid at 10 - 15℃; for 1h;	72%

: 1115-70-4
metformin hydrochloride

: 145-42-6
sodium taurocholate

: tauro-CA-metformin complex

Conditions

Conditions	Yield
In methanol at 20℃;	72%

: 145-42-6
sodium taurocholate

A: 107-35-7
Tau

B: 81-25-4
cholic acid

Conditions

Conditions	Yield
With ethylenediaminetetraacetic acid; chloylglycine hydrolase; 2-hydroxyethanethiol In phosphate buffer at 20℃; for 0.333333h; pH=8;	A n/a B 100 % Chromat.

: 145-42-6
sodium taurocholate

: 911-40-0
7-ketodeoxycholic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 100 percent Chromat. / chloylglycine hydrolase; β-mercaptoethanol; EDTA / aq. phosphate buffer / 0.33 h / 20 °C / pH 8 2: 8 percent / Sepharose-CL6B; 7β-hydroxysteroid dehydrogenase; TEA / NAD(+) / H2O / 120 h / 20 °C View Scheme

: 145-42-6
sodium taurocholate

: 2955-27-3
ursocholic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 100 percent Chromat. / chloylglycine hydrolase; β-mercaptoethanol; EDTA / aq. phosphate buffer / 0.33 h / 20 °C / pH 8 2: 80 percent / Sepharose-CL6B; 7β-hydroxysteroid dehydrogenase; TEA / NAD(+) / H2O / 120 h / 20 °C View Scheme

: 6117-25-5
N,N’-ethylenebismethacrylamide

: 145-42-6
sodium taurocholate

: 2-aminoethylmethacrylate hydrochloride

poly(2-aminoethyl methacrylate hydrochloride-co-ethylene bis methacrylamide-co-sodium taurocholate): poly(2-aminoethyl methacrylate hydrochloride-co-ethylene bis methacrylamide-co-sodium taurocholate)

Conditions

Conditions	Yield
With potassium persulfate In water at 65℃; for 18.5h; Product distribution / selectivity;

...Expand

: 145-42-6
sodium taurocholate

: 7585-39-9
β‐cyclodextrin

: 103419-28-9
C26H44NO7S(1-)*C42H70O35*Na(1+)

Conditions

Conditions	Yield
In water at 25℃; pH=7; Thermodynamic data; Concentration; phosphate buffer;

Raw Materials

107-35-7

81-25-4

Downstream Products

81-25-4

107-35-7

75-65-0

Total:132 Page 1 of 4 1 2 3 4 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 145-42-6

Consensus Reports

Reported in EPA TSCA Inventory.

Specification

The Sodium taurocholate, with the CAS registry number 145-42-6 and EINECS registry number 205-653-7, has the systematic name of sodium 2-{[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate. It belongs to the following product categories: Bile Acids; Biochemistry; Steroids. And the molecular formula of the chemical is C₂₆H₄₄NaO₇S. What's more, it should be stored at 0-6°C. In addition, it is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

The physical properties of Sodium taurocholate are as following: (1)ACD/LogP: 0.05; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): -3.38; (4)ACD/LogD (pH 7.4): -3.45; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 8; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 10; (12)Polar Surface Area: 110.75 Å².

You should be cautious while dealing with this chemical. It irritates eyes, respiratory system and skin. Therefore, you had better take the following instructions: Avoid contact with skin and eyes; Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].[O-]S(=O)(=O)CCNC(=O)CC[C@@H](C)[C@H]4CC[C@H]3[C@H]2[C@@H]([C@@]1([C@@H](C[C@H](O)CC1)C[C@H]2O)C)C[C@H](O)[C@@]34C
(2)InChI: InChI=1/C26H45NO7S.Na/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;/m1./s1
(3)InChIKey: JAJWGJBVLPIOOH-PNCITGCKBN

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rabbit	LDLo	intravenous	110mg/kg (110mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 52, Pg. 779, 1926.