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CAS No.: | 14521-96-1 |
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Name: | ETORPHINE |
Article Data: | 10 |
Molecular Structure: | |
Formula: | C25H33 N O4 |
Molecular Weight: | 411.541 |
Synonyms: | 6,14-Ethenomorphinan-7-methanol,4,5-epoxy-3-hydroxy-6-methoxy-a,17-dimethyl-a-propyl-, [5a,7a(R)]-;6,14-endo-Ethenotetrahydrooripavine, 7a-((R)-1-hydroxy-1-methylbutyl)- (8CI); (-)-Etorphine;19-Propylorvinol; 7a-Etorphine; Etorphine |
Density: | 1.3g/cm3 |
Melting Point: | 217°C |
Boiling Point: | 549.7°C at 760 mmHg |
Flash Point: | 286.2°C |
Safety: | Poison by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 62.16000 |
LogP: | 3.10150 |
Product Name: 7-α-Etorphine (CAS NO.14521-96-1)
Molecular Formula: C25H33NO4
Molecular Weight: 411.53g/mol
Mol File: 14521-96-1.mol
Einecs: 238-535-9
Boiling point: 549.7 °C at 760 mmHg
Flash Point: 286.2 °C
Surface Tension: 60.8 dyne/cm
Enthalpy of Vaporization: 87.29 kJ/mol
Vapour Pressure: 6.47E-13 mmHg at 25°C
XLogP3-AA: 3.1
H-Bond Donor: 2
H-Bond Acceptor: 5
7-α-Etorphine (CAS NO.14521-96-1) is often used to immobilize elephants and other large mammals. An etorphine antidote Large Animal Revivon contains mainly diprenorphine for animals and a human-specific naloxone-based antidote, which should be prepared prior to the etorphine.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
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mouse | LD50 | intraperitoneal | 200mg/kg (200mg/kg) | Agents and Actions, A Swiss Journal of Pharmacology. Vol. 6, Pg. 755, 1976. |
Poison by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
7-α-Etorphine ,its CAS NO. is 14521-96-1,the synonyms is : [5alpha,7alpha(R)]-4,5-Epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl-alpha-propyl-6,14-ethenomorphinan-7-methanol ; 19-Propylorvinol ; 6,14-Endo-Ethenotetrahydrooripavine, 7alpha-(1-hydroxy-1-methylbutyl)- ; 6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl-alpha-propyl-, [5alpha,7alpha(R)]- ; 6,7,8,14-Tetrahydro-7alpha-(1-hydroxy-1-methylbutyl)-6,14-endo-ethenooripavine ; 7,8-Dihydro-7-alpha-(1-(R)-hydroxy-1-methylbutyl)-O6-methyl-6,14-endo-ethenomorphine ; 7-alpha-(1-(R)-Hydroxy-1-methylbutyl)-6,14-endo-ethenotetrahydrooripavine ; 7alpha-Etorphine .