Reference

Purifn

Purifn. of poly-b-1?4-N-acetylglucosamine from microalgae for medicinal and cosmetic applications. Vournakis, John N.; Finkielsztein, Sergio; Pariser, Ernest R.; Helton, Mike (Marine Polymer Technologies, Inc., USA). U.S. US 5623064 A 22 Apr 1997, 89 pp., Cont.-in-part of U.S. Ser. No. 160,569. (English). (United States of America). CODEN: USXXAM. CLASS: ICM: C08B037-08. ICS: C12P019-26; A61K031-73. NCL: 536020000. APPLICATION: US 1994-347911 1 Dec 1994. PRIORITY: US 1993-160569 1 Dec 1993. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 26 The present invention relates to a purified, easily produced poly-b-1?4-N-acetylglucosamine (p-GlcNAc) polysaccharide species. The p-GlcNAc of the invention is a polymer of high mol. wt. whose constituent monosaccharide sugars are attached in a b-1?4 conformation, and which is free of proteins, and substantially free of single amino acids, and other org. and inorg. contaminants. In addn., derivs. and reformulations of p-GlcNAc are described. The present invention further relates to methods for the purifn. There are some commonly used reagents like 148411-57-8 in this article. of the p-GlcNAc of the invention from microalgae, preferably diatoms, as starting sources. Still further, the invention relates to methods for the derivatization and reformulation of the p-GlcNAc. Addnl., the present invention relates to the uses of pure p-GlcNAc, its derivs., and/or its reformulations. .