Reference

Perfume and/or flavoring materials

Perfume and/or flavoring materials. Naegeli, Peter (Givaudan, L., et Cie. S. A., Switz.). Ger. Offen. DE 2610238 23 Sep 1976, 20 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C07D307-94. PRIORITY: CH 75-3053 11 Mar 1975. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 17, 27 Theaspirane (I) [36431-72-8], which occurs in trace amts. in certain essential oils, has a fresh, fruity odor useful in perfumes and flavorings as principal component or modifier. For example, a vanilla flavoring contg. guaiacol 1.0, heliotropin 1.0, isoeugenol 2.0, p-hydroxybenzaldehyde 3.0, vanillin 20.0, ethylvanillin 120.0, I 3.0, and EtOH 850.0 parts had an odor superior to that of a similar compn. lacking I. To prepare I, .beta.-ionone [14901-07-6] was treated with isopropenyl acetate [108-22-5] to form 4-(2,6,6-trimethyl-2-cyclohexen-1-ylidene)-2-acetoxybut-2-ene [61693-39-8], reduced with NaBH4 to 4-(2,6,6-trimethyl-2-cyclohexen-1-ylidene)butan-2-ol [61693-40-1], and cyclized by refluxing with p-toluenesulfonic acid in C6H6.

Carotenogenesis: Possible mechanism of action of trisporic acid in Blakeslea trispora

Carotenogenesis: Possible mechanism of action of trisporic acid in Blakeslea trispora. Rao, Satya; Modi, V. V. (Fac. Sci., Maharaja Sayajirao Univ. Baroda, Baroda, India). Experientia, 33(1), 31-3 (English) 1977. CODEN: EXPEAM. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Trisporic acid (I) [11043-91-7] and .beta.-ionone [14901-07-6], stimulators of carotenogenesis in B. trispora, were competitive, suggesting that they have the same site of action. Since .beta.-ionone has been reported to act on the biochem. pathway of terpenoid synthesis between the conversion of 5-phosphomevalonate to dimethyl allyl pyrophosphate, I may well act by derepressing the enzymes involved in this conversion. The minus strain of B. trispora was selected as the test organism, because it does not produce I but carotene synthesis was stimulated by I.