CAS No.150-30-1,DL-3-Phenylalanine Suppliers

Products Categories

Pharmaceutical (130)
Food Additives (52)
Others (40)
Organic Chemicals (38)
Reagent (9)
Plant Extract (4)
Materials (1)
Basic Inorganic Chemicals (1)

Basic Information

Molecular Structure:
CAS No.:	150-30-1
Name:	DL-3-Phenylalanine
Article Data:	164

Formula:	C₉H₁₁NO₂
Molecular Weight:	165.192
Synonyms:	alpha-Aminohydrocinnamic acid, dl-;H-DL-Phe-OH;2-Amino-3-phenylpropionic acid, dl-;Phenylalanine DL-form;Alanine, phenyl-, DL- (8CI);DL-alpha-Amino-beta-phenylpropionic acid;(2R)-2-azaniumyl-3-phenyl-propanoate;
EINECS:	205-756-7
Density:	1.202 g/cm³
Melting Point:	266-267 °C
Boiling Point:	307.5 °C at 760 mmHg
Flash Point:	139.771 °C
Solubility:	14.11 g/L (25 °C) in water
Appearance:	white crystalline powder
Hazard Symbols:	Xi,C
Risk Codes:	36/37/38-34
Safety:	37/39-24/25-45-36/37/39-27-26
PSA:	63.32000
LogP:	1.34130

Synthetic route

: 3235-26-5
2-(N-acetylamino)-2-benzylpropanedioic diethyl ester

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
With hydrogenchloride; water at 90℃; for 0.166667h; Microwave irradiation;	98%
With water; hydrogen cation Heating;	82%
With hydrogen bromide anschliessend Erwaermen mit wss. Schwefelsaeure;
With sodium hydroxide anschliessend Erwaermen mit wss. Schwefelsaeure;
With hydrogenchloride In water at 110℃; Microwave irradiation;

: 63-91-2
L-phenylalanine

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
salicylaldehyde In acetic acid at 100℃; for 1h;	94%
With barium dihydroxide; water at 155 - 160℃;
With hydrogenchloride; ethanethiol at 110℃; Rate constant; various times;

: 100-39-0
benzyl bromide

: C21H15N3O3(2-)*Ni(2+)

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
With potassium hydroxide; C-7 In dichloromethane at 20℃;	90%

: 126181-40-6
2-(Benzhydryl-amino)-3-phenyl-propionic acid tert-butyl ester

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
palladium on activated charcoal In acetic acid Heating;	89%
Multi-step reaction with 2 steps 1: 60 percent / formic acid / 10percent Pd/C / methanol 2: trifluoroacetic acid View Scheme

: 2-Benzyl-2-benzyloxycarbonylamino-malonic acid dimethyl ester

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
With water; hydrogen cation Heating;	88%

: 2-[2-Benzoylamino-1-methoxy-eth-(Z)-ylideneamino]-3-phenyl-propionic acid

A: 150-30-1
Phenylalanine

B: 1205-08-9
methyl hippurate

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether Yields of byproduct given;	A n/a B 69%

: 2-[2-Benzoylamino-1-ethoxy-eth-(Z)-ylideneamino]-3-phenyl-propionic acid

A: 150-30-1
Phenylalanine

B: 1499-53-2
ethyl hippurate

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether	A n/a B 63%

: 154279-16-0
(±)-N-Boc-2-amino-2-benzylacetonitrile

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
With hydrogenchloride In methanol for 6h; Heating;	50%

: 81477-94-3
N-(diphenylmethylene)glycine tert-butyl ester

: 100-39-0
benzyl bromide

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
Stage #1: N-(diphenylmethylene)glycine tert-butyl ester; benzyl bromide With sodium hydroxide; (R)-2-amino-2'-hydroxy-1,1'-binaphthyl In dichloromethane at 20℃; for 1h; Stage #2: With hydrogenchloride In methanol; water Heating;	50%

: 140-10-3
(E)-3-phenylacrylic acid

: 150-30-1
Phenylalanine

Conditions

Conditions	Yield
With ammonium bicarbonate Ambient temperature; detonation; also with (NH4)2CO3;	45%
With ammonium bicarbonate Ambient temperature; detonation; also with (NH4)2CO3;	45%
With ammonium hydroxide; Anabaena variabilis phenylalanine ammonia lyase at 30℃; pH=9.5; Kinetics; Enzymatic reaction;
With ammonium hydroxide; phenylalanine ammonia-lyase from Anabaena variabilis N347A mutant In aq. buffer at 35℃; for 12h;
With phenylalanine ammonia lyase from Anabaena variabilis; ammonium carbamate at 30℃; for 22h; pH=9.9; Catalytic behavior; pH-value; Enzymatic reaction;	99 %Chromat.

Raw Materials

100-97-0

64-17-5

842-74-0

Downstream Products

738-75-0

89-24-7

Total:213 Page 1 of 6 1 2 3 4 5 6 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 150-30-1

History

In 1961,J. Heinrich Matthaei and Marshall W. Nirenberg discovered the genetic codon for phenylalanine was firstly . They pointed out that by using m-RNA to insert multiple uracil repeats into the bacterium E. coli, the bacterium produced a new protein consisting solely of repeated phenylalanine amino acids. This discovery caused the determination of the relationship between RNA and amino acids, which was fundamental to the understanding of the Genetic Code.

Consensus Reports

Dl-phenylalanine is reported in EPA TSCA Inventory.

Specification

The IUPAC name of DL-Phenylalanine is 2-amino-3-phenylpropanoic acid. With the CAS registry number 150-30-1, it is also named as Phenylalanine DL-form. The product's categories are Food & Feed Additives; Amino Acids Series; Amino Acids; Chiral; Organic Acids; Phenylalanine [Phe, F]; alpha-Amino Acids; Biochemistry; Amino Acids; Phenlalnine; Amino Acid; Food Additive; Pharmaceutical Intermediate. Besides, it is white crystalline powder, which should be sealed in a cool, dry place. It is stable, and incompatible with strong oxidizing agents. In addition, its molecular formula is C₉H₁₁NO₂ and molecular weight is 165.19.

The other characteristics of this product can be summarized as: (1)EINECS: 205-756-7; (2)ACD/LogP: 0.24; (3)# of Rule of 5 Violations: 0; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 3; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 4; (11)Index of Refraction: 1.576; (12)Molar Refractivity: 45.493 cm³; (13)Molar Volume: 137.437 cm³; (14)Surface Tension: 53.597 dyne/cm; (15)Density: 1.202 g/cm³; (16)Flash Point: 139.771 °C; (17)Melting point: 266-267 °C; (18)Water solubility: 14.11 g/L (25 °C); (19)Enthalpy of Vaporization: 57.873 kJ/mol; (20)Boiling Point: 307.5 °C at 760 mmHg; (21)Vapour Pressure: 0 mmHg at 25 °C.

Preparation of DL-Phenylalanine: this chemical can be prepared by the reaction of Acetyl-L-phenylalanine with HCl. Furthermore, it is produced by acetylamino-benzyl-malonic acid diethyl ester.

This reaction needs H⁺, water by heating. The yield is 82 %.

Uses of DL-Phenylalanine: this chemical is used as a dietary supplement and as a nutritional supplement for its supposed analgesic and antidepressant activities. Additionally, it can react with acetic acid anhydride to get N-(1-benzyl-2-oxo-propyl)-acetamide.

This reaction needs pyridine by heating. The yield is 76 %.

When you are using this chemical, please be cautious about it as the following: it may cause burns. It is also irritating to eyes, respiratory system and skin. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear suitable protective clothing, gloves and eye/face protection to avoid contact with skin and eyes. Moreover, please take off immediately all contaminated clothing. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure.
(1)Canonical SMILES: C1=CC=C(C=C1)CC(C(=O)O)N
(2)InChI: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)
(3)InChIKey: COLNVLDHVKWLRT-UHFFFAOYSA-N