Detail of "150375-75-0"
- MSDS Download
- CAS Number:
- 150375-75-0
- Name:
2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-,(2S)-
- Molecular Structure:
![Molecular Structure of 150375-75-0 (2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-,(2S)-)](http://www.lookchem.com/300w/2010/0619/150375-75-0.jpg)
- Formula:
- C28H27 Cl2 N3 O7 S
- Molecular Weight:
- 620.50088
- Synonyms:
- 2-Pyrrolidinecarboxamide,1-[[5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-,[2R-[2a(S*),3b]]-; Relcovaptan; SR 49059
- Density:
- 1.499g/cm3
- Boiling Point:
- 868°Cat760mmHg
- Flash Point:
- 478.8°C
2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-,(2S)-
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Reference
- Comparative pharmacology of bovine, human and rat vasopressin receptor isoforms
- Some chemicals with cas registry numbers like 150375-75-0 and 50-56-6 are also used. Comparative pharmacology of bovine, human and rat vasopressin receptor isoforms. Andres, Miriam; Pena, Ana; Derick, Sylvain; Raufaste, Daniele; Trojnar, Jerzy; Wisniewski, Kazimierz; Trueba, Miguel; Serradeil-Le Gal, Claudine; Guillon, Gilles (INSERM U 469, Montpellier 34094, Fr.). European Journal of Pharmacology, 501(1-3), 59-69 (English) 2004 Elsevier B.V. CODEN: EJPHAZ. ISSN: 0014-2999. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) In this study, we characterized the bovine vasopressin V1a, V1b, V2 receptor isoforms and compared their pharmacol. properties to those of corresponding rat and human vasopressin receptor subtypes. Specific binding sites of high affinity for vasopressin were found in all bovine tissues tested (kidney, liver and pituitary). Using a large series of recent peptidic and non-peptidic selective vasopressin agonists or antagonists, we demonstrated the presence of vasopressin V2, V1a or V1b receptors in the kidney, liver and pituitary bovine tissues, resp. This extensive characterization of bovine vasopressin receptor isoforms validates the pharmacol. vasopressin receptor classification earlier established for the rat and human species. As expected, the bovine vasopressin receptors look much more like human receptors than rat ones. Interestingly, among the three vasopressin receptor isoforms studied, the vasopressin V1b receptor subtype is the best conserved for the three species studied. .
- Clinical application of arginine vasopressin receptor antagonists
- Clinical application of arginine vasopressin receptor antagonists. 185913-79-5 and 150375-75-0 are also occured in this study. Ishikawa, San-e (Department of Medicine, Omiya Medical Center, Jichi Medical School, Saitama 330-8503, Japan). Naibunpi, Tonyobyoka, 16(5), 470-475 (Japanese) 2003 Kagaku Hyoronsha. CODEN: NATOFF. ISSN: 1341-3724. DOCUMENT TYPE: Journal; General Review CA Section: 1 (Pharmacology) A review. Clin. application of arginine vasopressin receptor antagonists such as OPC-21268, OPC-31260, SR-49059, SR-121463A, YM-087, and OPC-41061 in the treatment of hyponatremia and water retention is reviewed. .