Products Categories
CAS No.: | 15128-52-6 |
---|---|
Name: | 1,2,3,9-Tetrahydro-4(H)-carbazol-4-one |
Article Data: | 71 |
Molecular Structure: | |
Formula: | C12H11NO |
Molecular Weight: | 185.225 |
Synonyms: | Carbazol-4(1H)-one,2,3-dihydro- (6CI,7CI,8CI);1,2,3,4-Tetrahydrocarbazol-4-one;1,2-Dihydro-4(3H)-carbazolone;2,3-Dihydrocarbazol-4(1H)-one;4-Oxo-1,2,3,4-tetrahydrocarbazole; |
EINECS: | 604-791-9 |
Density: | 1.275 g/cm3 |
Melting Point: | 224-226 ºC |
Boiling Point: | 386.3 ºC at 760 mmHg |
Flash Point: | 194.5 ºC |
Appearance: | white crystal powder |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 26-36 |
PSA: | 32.86000 |
LogP: | 2.68690 |
3-[(2-iodophenyl)amino]cyclohex-2-en-1-one
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With tetrabutyl-ammonium chloride; sodium acetate; tris-(o-tolyl)phosphine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 0.5h; Heck reaction; Irradiation; | 95% |
With potassium hydroxide; copper(l) iodide; L-proline In dimethyl sulfoxide at 90℃; for 24h; | 92% |
With cyclodextrin-grafted silica-supported Pd nanoparticles at 100℃; for 1h; Heck Reaction; Green chemistry; | 85% |
methyl 6-(2-nitrophenyl)-5-oxohexanoate
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With hydrogenchloride; iron In water at 110℃; for 0.333333h; Inert atmosphere; | 92% |
1,2,3,4-tetrahydrocarbazole
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; water at 0℃; | 91% |
With nitrosonium perchlorate In water; acetonitrile for 1h; | 79% |
With 2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate In water; acetonitrile for 1h; Mechanism; Product distribution; other indole derivatives and nitrosonium salts, var. solvents; | 71% |
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With hydrogenchloride; titanium(III) chloride In acetone at 22℃; for 16h; Reagent/catalyst; Temperature; Solvent; | 91% |
cyclohexane-1,3-dione monophenylhydrazone
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With trifluoroacetic acid In acetic acid for 3h; Heating; | 90% |
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane at 20℃; for 0.5h; Cooling with ice; | 90% |
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With trifluoroacetic acid for 24h; Reflux; Inert atmosphere; | 90% |
1,2,3,4-tetrahydrocarbazole
A
1,2,3,9-tetrahydro-4H-carbazol-4-one
B
1-oxo-2,3,4,9-tetrahydrocarbazole
Conditions | Yield |
---|---|
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; water at 0 - 20℃; for 5.5h; | A 89% B 2% |
phenylhydrazine hydrochloride
1,3-cylohexanedione
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With 1-(3-sulfopropyl)pyridinium p-toluenesulfonate In water at 100℃; for 0.25h; | 89% |
Stage #1: phenylhydrazine hydrochloride; 1,3-cylohexanedione In acetonitrile at 80 - 85℃; Fischer Indole Synthesis; Stage #2: With hydrogenchloride In water at 90 - 95℃; Fischer Indole Synthesis; | 18% |
4-(1H-indol-2-yl)butanoic acid
1,2,3,9-tetrahydro-4H-carbazol-4-one
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In water; toluene for 12h; Reflux; Inert atmosphere; | 88% |
What can I do for you?
Get Best Price
The Molecular Structure of 1,2,3,9-Tetrahydro-4(H)-carbazol-4-one (CAS NO.15128-52-6):
Systematic Name: 1,2,3,9-Tetrahydro-4H-carbazol-4-one
Empirical Formula: C12H11NO
Molecular Weight: 185.2218
Product Categories: Miscellaneous; (intermediate of carvedilol and ondansetron); Heterocyclic Compounds; Heterocycles
Appearance: white powder
Nominal Mass: 185
Average Mass: 185.2218
Monoisotopic Mass: 185.084064
Index of Refraction: 1.689
Molar Refractivity: 55.44 cm3
Molar Volume: 145.1 cm3
Surface Tension: 59.9 dyne/cm
Density: 1.275 g/cm3
Flash Point: 194.5 °C
Enthalpy of Vaporization: 63.52 kJ/mol
Boiling Point: 386.3 °C at 760 mmHg
Melting Point: 224-226 °C
Vapour Pressure: 3.59E-06 mmHg at 25 °C
It can be used as a carbazole derivative with antimycobacterial activity.
Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing
1,2,3,9-Tetrahydro-4(H)-carbazol-4-one (CAS NO.15128-52-6) is also called as Rarechem ak ma k053 ; 4-Oxo-1,2,3,4-tetrahydrocarbazole ; 1,2,3,4-Tetrahydro-4h-carbazole-4-one ; 1,2,3,4-Tetrahydro-4-oxo-carbazole ; 1,2,3,4-Tetrahydro-9h-carbazole-4-one ; 1,2,3,9-Tetrahydro-4(h)-carbazol-4-one ; 1,2,3,9-Tetrahydro-9[h]-carbazole-4-one .