Detail of > 152-47-6
- CAS Number:
- 152-47-6
- Name:
Benzenesulfonamide,4-amino-N-(3-methoxy-2-pyrazinyl)-
- Superlist Name:
- Sulfalen
- Formula:
- C11H12N4O3S
- Molecular Structure:
- Synonyms:
- Benzenesulfonamide,4-amino-N-(3-methoxypyrazinyl)- (9CI);Sulfanilamide, N1-(3-methoxypyrazinyl)-(8CI);2-Sulfanilamido-3-methoxypyrazine;3-Methoxy-2-sulfapyrazine;3-Methoxypyrazinesulfanilamide;AS 18908;Dalysep;
- Molecular Weight:
- 280.30
- EINECS:
- 205-804-7
- Density:
- 1.465 g/cm3
- Melting Point:
- 174~178 °C
- Boiling Point:
- 488.6 °C at 760 mmHg
- Flash Point:
- 249.3 °C
- Solubility:
- Hardly soluble in water, slightly soluble in ethanol, ethyl ether and propyl ether
- Appearance:
- White or slightly yellow crystal powder
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Reference
- Relation of the pharmacokinetics of sulfalene to its dosage form
- Relation of the pharmacokinetics of sulfalene to its dosage form. Neugodova, N. P.; Geitman, I. Ya.; Kivman, G. Ya. (Nauchno-Issled. Inst. Stand. Kontrolyu Lek. Sredstv, Moscow, USSR). Khim.-Farm. Zh., 12(7), 35-9 (Russian) 1978. CODEN: KHFZAN. ISSN: 0023-1134. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Blood and organ levels of sulfalene (I) [152-47-6] in rats were higher after i.m. of its methylglucamine salt [62907-78-2] than after oral administration of its free form. Max. concns. of I in blood and organs occurred within 15 min postadministration. Highest tissue levels were obsd. in liver followed by lung, heart, kidney, spleen, and brain.
- The possibility of the jet pulverization of sulfalene
- The possibility of the jet pulverization of sulfalene. Ezerskii, M. L.; Savitskaya, A. V. (BIKhS, Moscow, USSR). Khim.-Farm. Zh., 20(11), 1397-8 (Russian) 1986. CODEN: KHFZAN. ISSN: 0023-1134. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Jet pulverization is a suitable method for prepn. of powders of a hardly sol. drug sulfalene [152-47-6] for manuf. of suspensions. By jet pulverization, the surface area of the powder increased from 0.2-10 m2/g, having av. particle size 4 mm.
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