CAS No.1524-88-5,Flurandrenolide Suppliers,MSDS download

Products Categories

Pharmaceutical (37)
Organic Chemicals (9)
Others (5)
Basic Inorganic Chemicals (2)
Reagent (1)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	1524-88-5
Name:	Flurandrenolide
Article Data:	12

Formula:	C₂₄H₃₃FO₆
Molecular Weight:	436.521
Synonyms:	Pregn-4-ene-3,20-dione,6a-fluoro-11b,16a,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone(7CI,8CI);33379;6a-Fluoro-11b,21-dihydroxy-16a,17a-(isopropylidenedioxy)pregn-4-ene-3,20-dione;6a-Fluoro-16a-hydroxyhydrocortisone 16,17-acetonide;Alondra F;Cordran;Drenison;Drocort;Fluadrenolone;Fludroxycortide;Fluorandrenolone;Fluorandrenolone acetonide;Fluoroandrenolone acetonide;Flurandrenolide;Flurandrenolone;Flurandrenolone acetonide;Haelan;HaldroneF;L 33379;Sermaka;
EINECS:	216-196-8
Density:	1.314 g/cm³
Melting Point:	247-255°
Boiling Point:	578.75 °C at 760 mmHg
Flash Point:	303.817 °C
Solubility:	295mg/L(25 oC)
PSA:	93.06000
LogP:	2.49870

Synthetic route

: 3385-03-3, 3870-63-1, 79284-83-6
flunisolide

: 1524-88-5
flurandrenolide

Conditions

Conditions	Yield
With Wilkinson's catalyst; hydrogen In ethanol; toluene for 65h; Ambient temperature;	76%
(tris(triphenylphosphine)rhodium) chloride In ethanol; chloroform; toluene
(tris(triphenylphosphine)rhodium) chloride In ethanol; chloroform; toluene

: 1524-88-5
flurandrenolide

: 123-72-8
butyraldehyde

A: (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS,12S)-12-Fluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a-dimethyl-8-propyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

B: (4aR,4bS,5S,6aS,6bS,8S,9aR,10aS,10bS,12S)-12-Fluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a-dimethyl-8-propyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

Conditions

Conditions	Yield
With hydrogenchloride at -15 - -10℃; for 2h;	A 39% B 27%

...Expand

: 1524-88-5
flurandrenolide

: 543-80-6
barium(II) acetate

: 4533-89-5
21-(acetyloxy)-6α-fluoro-11β-hydroxy-16α,17-<(1-methylethylidene)bis(oxy)>pregna-1,4-diene-3,20-dione

Conditions

Conditions	Yield
1.) Corynebacterium simplex, DMF, 20 h, 2.) glacial acetic acid, acetic anhydride, room temp., 24 h; Yield given. Multistep reaction;

: 1524-88-5
flurandrenolide

: 75578-60-8
6α-Fluoro-16α,17α-isopropylidenedioxandrost-4-en-11β-ol-3-one-17β-carboxylic acid

Conditions

Conditions	Yield
With potassium hydroxide; oxygen In methanol; dichloromethane for 6h; Ambient temperature; Yield given;

: 1524-88-5
flurandrenolide

: 112-67-4
n-hexadecanoyl chloride

: 144653-70-3
6α-Fluoro-11β-hydroxy-16α,17α-[(1-methylethylidene)bis(oxy)]-21-palmitoyloxypregn-4-ene-3 20-dione

Conditions

Conditions	Yield
In 1,4-dioxane; pyridine; ethanol; n-heptane; chloroform

Raw Materials

1526-01-8

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:54 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1524-88-5

Specification

The Flurandrenolide, with the CAS registry number 1524-88-5, is also known as 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with acetone. This chemical's molecular formula is C₂₄H₃₃FO₆ and formula weight is 436.52. What's more, its systematic name is called (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS,12S)-12-Fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol -2-one.

Physical properties about this chemical are: (1)ACD/LogP: 2.05; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.05; (4)ACD/LogD (pH 7.4): 2.05; (5)ACD/BCF (pH 5.5): 21.17; (6)ACD/BCF (pH 7.4): 21.17; (7)ACD/KOC (pH 5.5): 309.43; (8)ACD/KOC (pH 7.4): 309.43; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 71.06 Å²; (13)Index of Refraction: 1.572; (14)Molar Refractivity: 109.44 cm³; (15)Molar Volume: 332.3 cm³; (16)Surface Tension: 52.6 dyne/cm; (17)Density: 1.31 g/cm³; (18)Flash Point: 303.8 °C; (19)Enthalpy of Vaporization: 99.45 kJ/mol; (20)Boiling Point: 578.7 °C at 760 mmHg; (21)Vapour Pressure: 8.35E-16 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C1\C=C5/[C@](C)(CC1)[C@@H]2[C@H]([C@H]3[C@](C[C@@H]2O)([C@@]4(OC(O[C@@H]4C3)(C)C)C(=O)CO)C)C[C@@H]5F
(2)InChI: InChI=1/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
(3)InChIKey: POPFMWWJOGLOIF-XWCQMRHXBO