Detail of "154801-30-6"

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Chemical constituents of the fungus Leccinum extremiorientale

Chemical constituents of the fungus Leccinum extremiorientale. Gao, Jin-Ming; Shen, Jie; Zhang, An-Ling; Zhu, Wei; Zhang, Xin; Liu, Ji-Kai (Coll. Life Sci., Northwest Sci. 57-87-4 and 154801-30-6 are also occured in this study. Technol. univ. Agriculture and Forestry, Yangling 712100, Peop. Rep. China). Youji Huaxue, 23(8), 853-857 (Chinese) 2003 Kexue Chubanshe. CODEN: YCHHDX. ISSN: 0253-2786. DOCUMENT TYPE: Journal CA Section: 10 (Microbial, Algal, and Fungal Biochemistry) Thirteen chem. constituents were isolated from the fruiting bodies of basidiomyctes Leccinum extremiorientale, and their structures were elucidated by spectral and phys.-chem. data as: ergosta-7,22-dien-3b,5a,6b-triol (1), ergosterol peroxide (2), ergosterol (3), ergosta-4,6,8(14),22-tetraen-3-one (4), ergosta-5,7-dien-3b-ol (5), palmitic acid (6), (2S,3S,4R,2'R)-2-(2'-hydroxytetracosanoylanmino)octadecane-1,3,4-tri ol (7), cerebroside B (8), cerebroside D (9), uracil (10), inosine (11), adenosine (12) and D-allitol (13). The NMR data of compds. 8 and 9 were completely assigned by 2D-NMR techniques, including 1H-1H COSY, HMBC and HMQC. Compds. 2, 7 and 8 at concn. of 100 mg/mL showed selectively inhibitory activity against phospholipase A2 (PLA2) secreted from Crotalus adanmenteus venom, but inactive against PLA2 of bee venom (Apis mellifcra). In addn., the methanol-chloroform sol. ext. of this fungus also showed 67% antifeedant rate against Leucaninia separata and caused 55% mortality against Plutella xylostella after three-day application. .