Detail of "15574-96-6"

Reference

Piperidine derivatives for treating depression in aged patients due to long illness

Piperidine derivatives for treating depression in aged patients due to long illness. (Sandoz A.-G., Switz.). Japan. Kokai JP 52057333 11 May 1977 Showa, 3 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K031-645. PRIORITY: GB 75-44878 30 Oct 1975. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Compns. contg. the 4-(9.10-dihydro-4H-benzo(4,5]cyclohepta[1,2-b]thiophene-4-ylidene)-1- alkylpiperidines I (R = lower alkyl) as active ingredients are effective in treating depression due to long illness in aged patients. I together with carriers and binders can be made into tablet, granule, powder and capsule prepns. Thus, prepns. contg. 4-(9.10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ylidene)-1- methylpiperidine [15574-96-6] are highly effective for depressed, aged patients as evaluated by the Zung and Klerman-Hamilton scale.

Analgesic compositions containing piperidine derivatives

Analgesic compositions containing piperidine derivatives. (Sandoz A.-G., Switz.). Japan. Kokai JP 52057334 11 May 1977 Showa, 3 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K031-645. PRIORITY: GB 75-45634 3 Nov 1975. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Analgesic compns. contain the piperidine derivs. I (R = lower alkyl) or their salts as active ingredients in addn. to carriers. I can be made into granule, powder, tablet, or capsule prepns. The ED50 value of 4-(9.10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ylidene)-1- methylpiperidine [15574-96-6] was 14.5-22.3 mg/kg for rats after s.c. administration.