Detail of "15588-95-1"

CAS Number:
15588-95-1
Name:
Benzeneethanamine,2,5-dimethoxy-a,4-dimethyl-
Molecular Structure:
Formula:
C12H19 N O2
Molecular Weight:
223.35
Synonyms:
Phenethylamine,2,5-dimethoxy-a,4-dimethyl-(8CI);(RS)-DOM;(?à)-1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane;(?à)-1-(4-Methyl-2,5-dimethoxyphenyl)-2-aminopropane;(?à)-2,5-Dimethoxy-4-methylamphetamine;(?à)-DOM;1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane;2,5-Dimethoxy-4-methylamphetamine;2,5-Dimethoxy-4-methylphenylisopropylamine;2,5-Dimethoxy-a,4-dimethylphenylethylamine;2,5-Dimethoxymethylamphetamine;2',5'-Dimethoxy-4'-methylamphetamine;4-Methyl-2,5-dimethoxy-a-methylphenethylamine;4-Methyl-2,5-dimethoxyamphetamine;DOM;STP;STP(hallucinogen);dl-2,5-Dimethoxy-4-methylamphetamine;dl-4-Methyl-2,5-dimethoxyamphetamine;26011-50-7;
Density:
0.998g/cm³
Boiling Point:
322.7°Cat760mmHg
Flash Point:
162.9°C
Hazard Symbols:
A poison by ingestion.
Safety:
A poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NO_x. Details

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Studies on radioimmunoassay for 2,5-dimethoxy-4-methylamphetamine: Studies on radioimmunoassay for 2,5-dimethoxy-4-methylamphetamine. Nagamatsu, Kunisuke; Kido, Yasumasa; Urakubo, Goro (Natl. Inst.Several substances are used for example 15588-95-1 which is its cas registry number. Hyg. Sci., Tokyo, Japan). Chem. Pharm. Bull., 25(12), 3390-4 (English) 1977. CODEN: CPBTAL. ISSN: 0009-2363. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 15 A sensitive and sp. method of radioimmunoassay for 2,5-dimethoxy-4-methylamphetamine (DOM)(I) [15588-95-1] was developed, using anti-DOM antiserum obtained by immunizing guinea pigs with DOM glutaraldehyde-HSA conjugate and 122I-N succinyl tyrosine Me ester (125I-DOM) [66163-90-4] as a labeled hapten. DOM, 125I-DOM and antibody came up to equil. over 15 h at 4° of the incubation time in the radioimmunoassay system at pH 7.4 in phosphate buffer. Bound 125I-DOM was pptd. with satd. (NH4)2SO4 and the radioactivity of the bound labeled hapten was detd. by g-counting. The displacement curve was linear when the percentage binding of 125I-DOM was plotted against logarithmic increase of unlabeled DOM from 1 to 100 ng. The antiserum showed less affinity for various phenylisopropylamine derivs. and biogenic amines, and there was no interfering substance in a normal serum. .

Discriminative stimulus properties of the serotonin agonist 1-(3-trifluoromethylphenyl)piperazine (TFMPP): Discriminative stimulus properties of the serotonin agonist 1-(3-trifluoromethylphenyl)piperazine (TFMPP). Glennon, Richard A.; McKenney, J. D.; Young, Richard (Med. Coll. Virginia, Virginia Commow. Univ., Richmond, VA 23298, USA). Life Sci., 35(14), 1475-80 (English) 1984. CODEN: LIFSAK. ISSN: 0024-3205. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 2 Using a std. 2-lever drug discrimination procedure, rats were trained to discriminate 1.0 mg/kg of the 5-HT agonist 1-(3-trifluoromethylphenyl)piperazine (TFMPP)(I) [15532-75-9] from saline. Once trained, the animals displayed a dose-related decrease in discriminative performance upon administration of lower doses of TFMPP. Tests of stimulus generalization were performed using a purported 5-HT agonist RU-24,969 [66611-26-5] and 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) [15588-95-1]. TFMPP produced stimulus effects similar to those of RU-24,969, these effects were dissimilar to those of DOM. Apparently, the discriminative stimulus effects of TFMPP involve a 5-HT1-related mechanism.