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CAS No.: | 1605-89-6 |
---|---|
Name: | Bolasterone |
Molecular Structure: | |
Formula: | C21H32 O2 |
Molecular Weight: | 316.484 |
Synonyms: | Androst-4-en-3-one,17b-hydroxy-7a,17-dimethyl- (7CI,8CI);Testosterone, 7a,17-dimethyl-(6CI); 17b-Hydroxy-7a,17-dimethylandrost-4-en-3-one;17b-Hydroxy-7a,17a-dimethylandrost-4-ene-3-one; 7a,17a-Dimethyl-17b-hydroxyandrost-4-en-3-one; 7a,17a-Dimethyltestosterone; Bolasterone; Myagen; NSC 66233;U 19763 |
Density: | 1.09g/cm3 |
Melting Point: | 163-165° |
Boiling Point: | 441°C at 760 mmHg |
Flash Point: | 188°C |
PSA: | 37.30000 |
LogP: | 4.51530 |
6-Dehydromethyltestosterone
methylmagnesium bromide
A
bolasterone
B
calusterone
Conditions | Yield |
---|---|
With tetrahydrofuran; copper(l) chloride |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrachloro-<1,4>benzoquinone 2: CuCl; THF View Scheme |
6-Dehydromethyltestosterone
methylmagnesium bromide
A
bolasterone
B
calusterone
Conditions | Yield |
---|---|
With tetrahydrofuran; copper(l) chloride |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetrachloro-<1,4>benzoquinone 2: CuCl; THF View Scheme |
Conditions | Yield |
---|---|
With sulfuric acid; methyllithium; lithium; toluene-4-sulfonic acid; triethylamine In methanol; acetone |
bolasterone
Conditions | Yield |
---|---|
With sulfur trioxide pyridine complex In N,N-dimethyl-formamide for 1h; Ambient temperature; |
Conditions | Yield |
---|---|
(i) Et2O, THF, (ii) aq. HCl, acetone; Multistep reaction; |
bolasterone
Conditions | Yield |
---|---|
(i) LiAlH4, THF, (ii) aq. HCl, acetone; Multistep reaction; |
bolasterone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sulfur trioxide pyridine complex / dimethylformamide / 1 h / Ambient temperature 2: 1percent aq. K2CO3 / dimethylformamide / 1 h / 60 °C 3: trimethylsilylimidazole / 0.17 h / 60 °C View Scheme |
bolasterone
17-epibolasterone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sulfur trioxide pyridine complex / dimethylformamide / 1 h / Ambient temperature 2: 1percent aq. K2CO3 / dimethylformamide / 1 h / 60 °C View Scheme |