CAS No.1609-47-8,Diethyl pyrocarbonate Suppliers,MSDS download

Products Categories

Pharmaceutical (60)
Others (26)
Organic Chemicals (25)
Reagent (14)
Materials (1)
Catalyst and Auxiliary (1)
Dyestuff and Pigment (1)

Basic Information

Molecular Structure:
CAS No.:	1609-47-8
Name:	Diethyl pyrocarbonate
Article Data:	20

Formula:	C₆H₁₀O₅
Molecular Weight:	162.142
Synonyms:	Dicarbonicacid, diethyl ester (9CI);Formic acid, oxydi-, diethyl ester (8CI);Pyrocarbonic acid diethyl ester (6CI);Baycovin;DEPC;Dekapex;Diethyldicarbonate;Diethyl oxydiformate;Piref;Ue 5908;carbonic acid, ethoxycarbonyl ethyl ester;Dicarbonic acid diethyl ester;Oxydiformic acid diethyl ester;
EINECS:	216-542-8
Density:	1.15 g/cm³
Melting Point:	69℃
Boiling Point:	201.3 °C at 760 mmHg
Flash Point:	69.4 °C
Solubility:	slow decomposition in water
Appearance:	colorless liquid
Hazard Symbols:	Xn
Risk Codes:	36/37/38-20/21/22
Safety:	26-36-37/39
Transport Information:	UN 2810
PSA:	61.83000
LogP:	1.31600

Synthetic route

: 541-41-3
chloroformic acid ethyl ester

: 1609-47-8
diethyl dicarbonate

Conditions

Conditions	Yield
With sodium hydroxide; tetrabutylammomium bromide In dichloromethane at -10℃; for 1h;	93%

: 483-18-1, 522-99-6, 7005-82-5, 38241-16-6, 65910-27-2, 74059-23-7, 74111-75-4, 74111-76-5
(+-)-Emetin

: 67-66-3
chloroform

: 541-41-3
chloroformic acid ethyl ester

diluted KOH: diluted KOH

A: 1609-47-8
diethyl dicarbonate

B: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
oder anstatt Emetin mit tertiaeren Basen,entsteht noch das N-Carbaethoxy-Derivat der betreffenden tertiaeren Base;

...Expand

: 541-41-3
chloroformic acid ethyl ester

emetine hydrochloride: emetine hydrochloride

: 1609-47-8
diethyl dicarbonate

Conditions

Conditions	Yield
With potassium hydroxide; chloroform
With chloroform; 2,3-Dimethylaniline
With chloroform mit anderen tertiaeren Basen;

: 541-41-3
chloroformic acid ethyl ester

potassium-salt of carbonic acid monoethyl ester: potassium-salt of carbonic acid monoethyl ester

: 1609-47-8
diethyl dicarbonate

Conditions

Conditions	Yield
With toluene

: 64-17-5
ethanol

: 24424-99-5
di-tert-butyl dicarbonate

A: 27945-07-9
tert-butyl ethyl carbonate

B: 19935-69-4
Ethyl-tert-butylpyrocarbonat

C: 1609-47-8
diethyl dicarbonate

D: 105-58-8
Diethyl carbonate

Conditions

Conditions	Yield
With dmap In acetonitrile at 20℃; Product distribution; Further Variations:; Solvents; reaction times; Condensation;

...Expand

: 5536-61-8
sodium methacrylate

: 541-41-3
chloroformic acid ethyl ester

A: 760-93-0
methacryloyl anhydride

B: 1609-47-8
diethyl dicarbonate

C: 21982-91-2
carboethoxymethacrylic anhydride

D: 105-58-8
Diethyl carbonate

...Expand

: 541-41-3
chloroformic acid ethyl ester

: 124-30-1
1-aminooctadecane

: 1609-47-8
diethyl dicarbonate

Conditions

Conditions	Yield
With sodium hydroxide; magnesium sulfate; PEG 15 stearamine In water

: 50-24-8
prednisolon

: 1609-47-8
diethyl dicarbonate

: Prednisolone 21-ethylcarbonate

Conditions

Conditions	Yield
In acetone for 0.5h; Heating;	100%

: 50-23-7
HYDROCORTISONE

: 1609-47-8
diethyl dicarbonate

: Hydrocortisone-21-ethyl carbonate

Conditions

Conditions	Yield
In ethanol for 0.5h; Heating;	100%

: 50-28-2
estradiol

: 1609-47-8
diethyl dicarbonate

: 105660-13-7
17β-Estradiol-bis-ethyl carbonate

Conditions

Conditions	Yield
for 0.5h; Heating;	100%

Total:101 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1609-47-8

Consensus Reports

Reported in EPA TSCA Inventory.

Specification

The Diethyl dicarbonate, with the CAS registry number 1609-47-8 and EINECS registry number 216-542-8, has the IUPAC name of ethoxycarbonyl ethyl carbonate. It is a kind of moisture sensitive liquid, and should be stored at 2-8°C. And the molecular formula of this chemical is C₆H₁₀O₅.

The physical properties of Diethyl dicarbonate are as following: (1)ACD/LogP: 1.48; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.48; (4)ACD/LogD (pH 7.4): 1.48; (5)ACD/BCF (pH 5.5): 7.89; (6)ACD/BCF (pH 7.4): 7.89; (7)ACD/KOC (pH 5.5): 152.68; (8)ACD/KOC (pH 7.4): 152.68; (9)#H bond acceptors: 5; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 61.83 Å²; (13)Index of Refraction: 1.413; (14)Molar Refractivity: 35.14 cm³; (15)Molar Volume: 140.9 cm³; (16)Polarizability: 13.93×10^-24cm³; (17)Surface Tension: 33.9 dyne/cm; (18)Density: 1.15 g/cm³; (19)Flash Point: 69.4 °C; (20)Enthalpy of Vaporization: 43.75 kJ/mol; (21)Boiling Point: 201.3 °C at 760 mmHg; (22)Vapour Pressure: 0.31 mmHg at 25°C.

Uses of Diethyl dicarbonate: It can react with 2,2-dimethyl-2,5-dihydro-thiazole to produce 2,2-dimethyl-thiazole-3-carboxylic acid ethyl ester. This reaction will need reagent Pr₃N, and the solvent toluene. The reaction time is 144 hours with heating, and the yield is about 90%.

Diethyl dicarbonate can react with 2,2-dimethyl-2,5-dihydro-thiazole to produce 2,2-dimethyl-thiazole-3-carboxylic acid ethyl ester

You should be cautious while dealing with this chemical. It irritates eyes, respiratory system and skin, and it is also harmful by inhalation, in contact with skin and if swallowed. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OCC)OC(=O)OCC
(2)InChI: InChI=1/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
(3)InChIKey: FFYPMLJYZAEMQB-UHFFFAOYAU

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	oral	100mg/kg (100mg/kg)		FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 52, 1974.
dog	LD50	oral	500mg/kg (500mg/kg)		FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 52, 1974.
guinea pig	LCLo	inhalation	10ppm/1H (10ppm)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	FAO Nutrition Meetings Report Series. Vol. 51A, Pg. 67, 1972.
mouse	LCLo	inhalation	10ppm/1H (10ppm)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	FAO Nutrition Meetings Report Series. Vol. 51A, Pg. 67, 1972.
mouse	LD50	oral	1558mg/kg (1558mg/kg)		FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 52, 1974.
rabbit	LCLo	inhalation	10ppm/1H (10ppm)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	FAO Nutrition Meetings Report Series. Vol. 51A, Pg. 67, 1972.
rabbit	LD50	oral	500mg/kg (500mg/kg)		FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 52, 1974.
rat	LCLo	inhalation	10gm/m³/1H (10000mg/m³)		Zeitschrift fuer Lebensmittel-Untersuchung und-Forschung. Vol. 114, Pg. 292, 1961.
rat	LD50	intraperitoneal	47mg/kg (47mg/kg)		FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 52, 1974.
rat	LD50	oral	850mg/kg (850mg/kg)		FAO Nutrition Meetings Report Series. Vol. 51A, Pg. 67, 1972.