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16142-27-1

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Basic Information
CAS No.: 16142-27-1
Name: 3-Morpholinosydnonimine hydrochloride
Article Data: 2
Molecular Structure:
Molecular Structure of 16142-27-1 (3-Morpholinosydnonimine hydrochloride)
Formula: C6H11N4O2.Cl
Molecular Weight: 206.632
Synonyms: 3-Morpholinosydnoniminehydrochloride;Linsidomine chlorhydrate;Linsidomine hydrochloride;1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-, chloride (9CI);Sydnone imine, 3-(4-morpholinyl)-,monohydrochloride;Sydnone imine, 3-morpholino-, monohydrochloride (8CI);3-Morpholinosydnone imine monohydrochloride;
EINECS: 247-207-4
Density: 1.303 at 20℃
Melting Point: 186 °C
Solubility: soluble in water
Appearance: White crystalline solid
Safety: 24/25
PSA: 67.28000
LogP: -0.10950
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  • Molsidomine EP Impurity A HCl (3-(Morpholin-4-yl)-Sydnonimine HCl, Linsidomine HCl)

  • Casno:

    16142-27-1

    Molsidomine EP Impurity A HCl (3-(Morpholin-4-yl)-Sydnonimine HCl, Linsidomine HCl)

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Topbatt Chemical Co., Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutical Reference Standards and Stable Isotopes. Our Stable Isotopes produ

    Topbatt Chemical Co. Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutic

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  • Molsidomine EP impurity A

  • Casno:

    16142-27-1

    Molsidomine EP impurity A

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    Impurities from EP, CP, USP, JP, IP and independent R&D Package:10mg, 25mg, 50mg, 100mg, Other scale please send an equiry Application:For research and development purpose Port:Guangzhou

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Chemistry

Molecular Formula: C6H11N4O2.Cl
Molecular Weight: 206.63
Melting point: 186 ºC
EINECS: 247-207-4
Storage temp: -20°C
Water solubility: soluble
CAS Registry Number: 16142-27-1
Appearance: White Crystalline Solid
Synonyms: 3-(4-Morpholinyl)-sydnone imine hydrochloride;3-Morpholinosydnoimine HCL;3-Morpholinosydnoimine hydrochloride;3-Morpholinosydnonimin hydrochloride;5-Amino-3-morpholinyl-1,2,3-oxadiazolium chloride 
Following is the molecular structure of 3-Morpholinosydnonimin hydrochloride (CAS NO.16142-27-1):

Uses

 3-Morpholinosydnonimin hydrochloride (CAS NO.16142-27-1) is a metabolite of the vasodilator molsidomine and is considered to be a peroxynitrite releasing compound.

Production

 3-Morpholinosydnonimin hydrochloride (CAS NO.16142-27-1) can first used  4 - amino-morpholine by potassium cyanide, formaldehyde and cyanide methylation, to generate 4 - (cyanomethyl-amino) morpholine, and then sodium nitrite nitrosation of 4 - (cyanomethyl-N-nitroso-amino) do morpholine, the latter in hydrochloric acid methanol cyclization get this product.

Toxicity Data With Reference

1.    

orl-mus LD50:480 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),280.
2.    

ipr-mus LD50:315 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),280.
3.    

ivn-mus LD50:260 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 2 (1968),280.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl.
Safety Information of 3-Morpholinosydnonimin hydrochloride (CAS NO.16142-27-1):
Safety Statements: 24/25
S24/25:Avoid contact with skin and eyes.