Reference

Reactions of lithio derivatives of carboxylic acids

Reactions of lithio derivatives of carboxylic acids.Some chemicals with cas registry numbers like 60582-21-0 are also used. 1. 3-Methyl-2-butenoic acids. Parham William E.; Boykin, David W. (Paul M. Gross Chem. Lab., Duke Univ., Durham, N. C., USA). J. Org. Chem., 42(2), 260-3 (English) 1977. CODEN: JOCEAH. DOCUMENT TYPE: Journal CA Section: 23 (Aliphatic Compounds) Me2C:CBrCO2H with BuLi in THF at -100.degree.C gave a stable lithiovinyl intermediate which reacts with a variety of electrophiles (e.g., EtI, cyclohexanone, Ph2CO) to afford 2-alkylated derivs. in good yields. Reaction of 3-methyl-2-butenoic acid with BuLi and Me3CLi followed by protonation or alkylation is discussed. .

Novel syntheses of monosubstituted acetic,

Novel syntheses of monosubstituted acetic, .alpha.,.beta.-unsaturated, and .beta.,.gamma.-unsaturated acids via silylation, hydroboration, and oxidation of the ethynyl group of 1-alkynes and functionally substituted 1-alkynes. Zweifel, George; Backlund, Stephen J. (Dep. Chem., Univ. California, Davis, Calif., USA). J. Am. Chem. Soc., 99(9), 3184-5 (English) 1977. CODEN: JACSAT. DOCUMENT TYPE: Journal CA Section: 23 (Aliphatic Compounds) Section cross-reference(s): 29 Monohydroboration of RC.tplbond.CSiMe3 (R = Bu, tert-Bu, Ph, 1-cyclohexenyl, H2C:CMe, PrCH:CH) with dicyclohexylborane and oxidn. with alk. H2O2 gave <91% resp. RCH2CO2H. Similar treatment of Me(CH2)nCH(OSiMe3)C.tplbond.CSiMe3 (n = 2, 3) gave (E)-Me(CH2)nCH:CHCO2H.Except for chemicals metioned above, 1617-31-8 and 60216-46-8 are also used. .