CAS No.1619-34-7,3-Quinuclidinol Suppliers

Detail of "1619-34-7"

CAS Number:

1619-34-7

Name:

3-Quinuclidinol

Molecular Structure:

Formula:

C₇H₁₃NO

Molecular Weight:

127.21

Deleted CAS:

3684-26-2,29924-74-1

Synonyms:

3-Quinuclidinol (6CI,7CI,8CI);1-Azabicyclo[2.2.2]oct-3-yl alcohol;3-Hydroxy-1-azabicyclo[2.2.2]octane;3-Hydroxyquinuclidine;NSC 93905;dl-3-Quinuclidinol;

EINECS:

216-578-4

Density:

1.13 g/cm³

Melting Point:

220-223 °C(lit.)

Boiling Point:

206.9 °C at 760 mmHg

Flash Point:

97.7 °C

Solubility:

soluble in water

Appearance:

Crystalline solid

Hazard Symbols:

Risk Codes:

34-11

Safety:

26-36/37/39-45-16 Details

Transport Information:

UN 3263 8/PG 2

Reference

Preparation of 1-azabicycloalkanes and a7 nicotine receptor agonists: Preparation of 1-azabicycloalkanes and a7 nicotine receptor agonists. Fujio, Masakazu; Hashimoto, Kenji; Katayama, Jiro; Numata, Atsushi ( Mitsubishi Well Pharma K. K., Japan). Jpn. Kokai Tokkyo Koho JP 2002030084 A2 29 Jan 2002, 15 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: ICM: C07D453-02. ICS: A61K031-439; A61P025-18; A61P025-28; A61P043-00. APPLICATION: JP 2000-217709 18 Jul 2000. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1 Title compds. I [X = absent, O, S, NH; Y = CH2, CO; Z = (CH2)m; m = 1-2; n = 0-3; Ar = (un)substituted bicyclic arom. heterocyclyl, naphthyl], their optical isomers, or pharmaceutical salts are prepd. The compds. are useful for treatment of cognition disorder, dementia, schizophrenia, attention defect hyperactivity disorder, and Alzheimer's disease. 1-Azabicyclo[2.2.2]octan-3-ol-borane complex was reacted with 2-chloromethylbenzo[b]thiophene in the presence of NaH in DMF under ice-cooling for 1 h and treated with HCl at room temp. for 1 h to give 0.17 g 3-[(benzo[b]thiophen-2-yl)methoxy]-1-azabicyclo[2.2.2]octane hydrochloride hemihydrate showing good affinity to a7 nicotine receptor in vitro.

Preparation of 2-alkoxyphenylcarbamoyloxyquinuclidinium chlorides as topical anesthetics: Preparation of 2-alkoxyphenylcarbamoyloxyquinuclidinium chlorides as topical anesthetics. Durinda, Jan; Gregan, Fridrich; Kralova, Katarina; Racanska, Eva ( Farmaceuticka Fakulta UK; Prirodovedecka Fakulta UK, Slovakia).In this study， 151643-52-6 and 1619-34-7 are also used. Slovakia SK 278236 B6 8 May 1996, 3 pp. (Slovak). (Slovakia). CODEN: SLXXFO. CLASS: ICM: C07C271-38. ICS: C07D453-02. APPLICATION: SK 1992-2057 1 Jul 1992. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1 The title compds. [I; R = C1-8 alkyl], useful as topical anesthetics, were prepd. Thus, reaction of 2-hexyloxyphenyl isocyanate with 3-quinuclidinol in PhMe afforded 70% I [R = n-hexyl] which showed IC50 of 1.00 mM/L against oxygen formation in spinach chloroplasts suspension. .

Detail of "1619-34-7"

3-Quinuclidinol

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CAS No.1619-34-7 3-Quinuclidinol

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CAS No.1619-34-7 3-Quinuclidinol

CAS No.1619-34-7 3-Quinuclidinol

CAS No.1619-34-7 3-Quinuclidinol

CAS No.1619-34-7 3-Quinuclidinol

CAS No.1619-34-7 3-Quinuclidinol

CAS No.1619-34-7 3-Quinuclidinol

CAS No.1619-34-7 3-Quinuclidinol

Reference