Detail of "1625-91-8"

Reference

Lithiated benzyllithiums from chlorobenzyl chlorides by a DTBB-catalyzed lithiation

Lithiated benzyllithiums from chlorobenzyl chlorides by a DTBB-catalyzed lithiation. Gomez, Cecilia; Huerta, Fernando F.; Yus, Miguel (Facultad Ciencias, Univ. Alicante, Alicante E-03080, Spain). Tetrahedron Letters, 38(4), 687-690 (English) 1997 Elsevier. CODEN: TELEAY. ISSN: 0040-4039. DOCUMENT TYPE: Journal CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) The reaction of 2-, 3- or 4-chlorobenzyl chlorides with an excess of lithium and a catalytic amt. of DTBB (7 mol%) in the presence of different electrophiles [Me2CHCHO, tert-BuCHO, Et2CO, (CH2)5CO, PhCOMe, Me3SiCl] in THF at -50°C leads after hydrolysis with water, to the expected diols or disilylated compds.In this experiment, several chemicals are used like 187274-03-9 and 1625-91-8 EC6H4E [ E = Me2CHCHOH, Me3CCHOH, Et2COH, (CH2)5COH, PhC(OH)Me, Me3Si]. .

b-Functionalized organolithium compounds through a sulfur-lithium exchange

b-Functionalized organolithium compounds through a sulfur-lithium exchange. Foubelo, Francisco; Gutierrez, Ana; Yus, Miguel (Departamento de QUimica Organica, Facultad de Ciencias, Universidad de Alicante, Alicante E-03080, Spain).In this study，1625-91-8 is also used. Tetrahedron Letters, 38(27), 4837-4840 (English) 1997 Elsevier. CODEN: TELEAY. ISSN: 0040-4039. DOCUMENT TYPE: Journal CA Section: 21 (General Organic Chemistry) The successive reaction of b-hydroxy or b-amino thioethers HYCHR1CH2SPh (Y = O, NPh; R1 = H, Ph, n-C6H13) with n-butyllithium and an excess of lithium powder and a catalytic amt. of DTBB (4,4'-di-tert-butylbiphenyl) in THF at -78°C leads to the formation of the corresponding b-functionalized organolithium compds. LiYCHR1CH2Li, which by reaction with electrophiles [D2O, ButCHO, PhCHO, Me2CO, (CH2)5CO] at temps. ranging between -78 and 20°C yields, after hydrolysis with water, the expected functionalized alcs. or amines HYCHR1CH2E [E = D, ButCH(OH), etc.] in a regioselective manner. .