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CAS No.: | 1634-78-2 |
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Name: | MALAOXON |
Article Data: | 6 |
Molecular Structure: | |
Formula: | C10H19 O7 P S |
Molecular Weight: | 314.296 |
Synonyms: | Butanedioicacid, [(dimethoxyphosphinyl)thio]-, diethyl ester (9CI); Succinic acid, mercapto-,diethyl ester, S-ester with O,O-dimethyl phosphorothioate (7CI,8CI); Succinicacid, mercapto-, diethyl ester, dimethyl phosphate (6CI); Phosphorothioic acid,O,O-dimethyl ester, S-ester with diethyl mercaptosuccinate (6CI); DL-Malaoxon;Diethyl [(dimethoxyphosphino)thio]butanedioate; Diethyl mercaptosuccinateS-ester with O,O-dimethyl phosphorothioate; Liromat; Malaoxon; Malaoxone;Malathion oxon; Malathion-O-analog; Maloxon; O,O-DimethylS-1,2-bis(ethoxycarbonyl)ethyl phosphorothioate; Oxycarbophos |
Density: | 1.248±0.06 g/cm3(Predicted) |
Melting Point: | <20℃ |
Boiling Point: | 114 °C |
Flash Point: | -18 °C |
Hazard Symbols: | F,Xn,N,T |
Risk Codes: | 11-38-50/53-65-67-24/25 |
Safety: | Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and POx. |
PSA: | 123.24000 |
LogP: | 2.00540 |
IUPAC Name: Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate
Synonyms of Oxycarbophos (CAS NO.1634-78-2) : Butanedioic acid, ((dimethoxyphosphinyl)thio)-, diethyl ester (9CI) ; Diethyl 2-[(dimethoxyphosphoryl)sulfanyl]succinate ; Diethyl 2-[(dimethoxyphosphoryl)thio]succinate
InChI: InChI=1/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3
Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Alpha sort;H-MAlphabetic;M;MA - MD;Pesticides&Metabolites
CAS NO: 1634-78-2
Molecular Formula:C10H19O7PS
Molecular Weight :314.2924
Molecular Structure :
EINECS: 228-294-8
Index of Refraction: 1.469
Surface Tension: 41.4 dyne/cm
Density: 1.248 g/cm3
Flash Point: 181.2 °C
Enthalpy of Vaporization: 62.36 kJ/mol
Boiling Point: 376 °C at 760 mmHg
Vapour Pressure: 7.46E-06 mmHg at 25°C
Storage temp: 0-6°C
Solubility:Slightly water soluble.
Appearance : Oxycarbophos (CAS NO.1634-78-2) is colorless viscous oily liquid with a weak unpleasant odor.
Oxycarbophos (CAS NO.1634-78-2 is an active metabolite of Malathion. It is a widely used anticholinesterase phosphorothioate insecticide.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
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mouse | LD50 | intraperitoneal | 75mg/kg (75mg/kg) | World Review of Pest Control. Vol. 3, Pg. 28, 1964. | |
mouse | LD50 | oral | 215mg/kg (215mg/kg) | Journal of Agricultural and Food Chemistry. Vol. 28, Pg. 599, 1980. | |
rabbit | LD50 | skin | 119mg/kg (119mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | National Technical Information Service. Vol. OTS0534701, |
rat | LD50 | intraperitoneal | 17500ug/kg (17.5mg/kg) | Canadian Journal of Physiology and Pharmacology. Vol. 45, Pg. 621, 1967. | |
rat | LD50 | oral | 158mg/kg (158mg/kg) | Toxicology and Applied Pharmacology. Vol. 9, Pg. 408, 1966. |
NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-135 ,1979.
Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and POx.
Hazard Codes F,Xn,N,T
Risk Statements 11-38-50/53-65-67-24/25
R11:Highly flammable.
R24/25: Toxic in contact with skin and if swallowed
R38:Irritating to skin.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R65:Harmful: may cause lung damage if swallowed.
R67:Vapours may cause drowsiness and dizziness.
Safety Statements 60-61-62-45-36/37/39
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S62:If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label.
RIDADR 3018
RTECS WM8410000
HazardClass 6.1(b)
PackingGroup III
1.Air & Water Reactions: Malaoxon may be sensitive to prolonged exposure to air.
2.Reactivity Profile: A thioorganophosphate, ester. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
3.Fire Hazard : Malaoxon is probably combustible.