Detail of "16427-44-4"

CAS Number:
16427-44-4
Name:
Ethanol, 2-methoxy-,1-methanesulfonate
Superlist Name:
2-Methoxyethyl methanesulfonate
Molecular Structure:
Formula:
C4H10 O4 S
Molecular Weight:
154.18
Synonyms:
Ethanol,2-methoxy-, methanesulfonate (8CI,9CI);Methanesulfonic acid, 2-methoxyethylester (6CI);2-Methoxyethyl mesylate;2-Methoxyethyl methanesulfonate;Ethyleneglycol monomethyl ether methanesulfonate;b-Methoxyethyl methanesulfonate;

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N7-derivatives of mitomycin C: N7-derivatives of mitomycin C. Wong, Henry She Lai; Kaneko, Takushi; Doyle, Terrence William (Bristol-Myers Co., USA). Fr. Demande FR 2571373 A1 11 Apr 1986, 19 pp. (France) CODEN: FRXXBL. CLASS: ICM: C07D487-14. ICS: A61K031-40. ICI: C07D487-14, C07D207-14, C07D203-12. APPLICATION: FR 85-13072 3 Sep 1985. PRIORITY: US 84-659128 9 Oct 1984. DOCUMENT TYPE: Patent CA Section: 26 (Biomolecules and Their Synthetic Analogs) Section cross-reference(s): 1 The title compds. (I; R = H, Me, COR1; R1 = alkyl, aralkyl; E = electrophilic group) were prepd. as antitumor agents by deprotonation of mitomycin C (II) or its N1a substituted derivs., and treatment with an electrophile. Thus, II was treated with NaH in DMF and alkylated with MeOCH2O3SMe to give 19% I (E = CH2OMe, R = H) (III). In mice, 12.8 mg III/kg i.In this experiment, several chemicals are used like 16427-44-4 and 18742-02-4 p. inhibited murine leukemia P-388. .