Detail of "16867-03-1"

CAS Number:
16867-03-1
Name:
2-Amino-3-hydroxypyridine
Molecular Structure:
Formula:
C₅H₆N₂O
Molecular Weight:
110.12
Synonyms:
2-Amino-3-hydroxypyridin;3-Hydroxy-2-aminopyridine;3-Pyridinol, 2-amino;2-Aminopyridin-3-ol;3-Hydroxy-2-pyridinamine;
EINECS:
240-886-8
Density:
1.32 g/cm³
Melting Point:
168-172 °C(lit.)
Boiling Point:
385.2 °C at 760 mmHg
Flash Point:
186.8 °C
Appearance:
white to light yellow crystal powder
Hazard Symbols:
Xi,T,Xn
Risk Codes:
36/37/38-25-40
Safety:
26-45-37/39-28A-36-22 Details
Transport Information:
UN 2811

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Reference

Heavy metal complexes: Heavy metal complexes. 91-35-0 which is the cas registry number of one of substances is just one of reagents here. Back, Gerhard; Fasciati, Alfred (Ciba-Geigy A.-G., Switz.). Ger. Offen. DE 2745024 13 Apr 1978, 106 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C09B005-14. PRIORITY: LU 76-75958 8 Oct 1976. 91-35-0 is just another one chemical used in this study. DOCUMENT TYPE: Patent CA Section: 40 (Dyes, Fluorescent Whitening Agents, and Photosensitizers) Metal (Cu, Ni, Co, Cr) complexes are prepd. from monoazo compds. of general structure I, where R = H, Br, Cl, NO2, alkyl, alkoxy, or acylamino, R1 = H or alkyl, R2 = carboxy- or sulfo-substituted Ph or naphthyl, R3 = H or NH2, R4 = H, Cl, Br, CN, substituted or unsubstituted amino, SH, alkyl- or arylthio, sulfo, or arylsulfonyl, R5 = H, Cl, or Br, and n = 0 or 1. The complexes are fast dyes for wool and polyamide fibers. Thus, diazotization of 2-HO2CC6H4NHSO2C6H3(OH)NH2-4,3 [91-35-0], coupling with 2-amino-3-hydroxypyridine [16867-03-1], and treatment of the violet monoazo compd. (II) [66804-37-3] with CuSO4 gave the reddish violet to blue 1:1 Cu complex, a water-sol. powder dyeing polyamide fibers and wool fast blue shades. Approx. 60 other metal complex dyes were similarly prepd. ..

Actions of aminopyridines on guinea-pig ileum: Actions of aminopyridines on guinea-pig ileum. Moritoki, H.; Takei, M.; Nakamoto, N.; Ishida, Y. (Fac. Pharm. Sci., Univ. Tokushima, Tokushima, Japan). Arch. Int. Pharmacodyn. Ther., 232(1), 28-41 (English) 1978. CODEN: AIPTAK. ISSN: 0003-9780. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Aminopyridines at concns. of above 10-5 M caused dose-dependent and reproducible contractions of the guinea-pig ileum, their effects decreassing in the order: 3,4-diaminopyridine [54-96-6] > 4-aminopyridine [504-24-5] > 2-aminopyridine [504-29-0] 3 2,3-diaminopyridine [452-58-4] > 2-amino-3-hydroxypyridine [16867-03-1] 3 3-aminopyridine [462-08-8] > 2,6-diaminopyridine [141-86-6]. These contractions were selectively suppressed by atropine and tetrodotoxin, and were potentiated by eserine, but they were not affected by ganglion blocking agents or antihistaminics. The twitch response of the ileum induced by transmural stimulation was potentiated by aminopyridines at one tenth of the concns. inducing contractions. In high Ca medium, low concns. of aminopyridines evoked spontaneous and rhythmic twitch-like contractions, which were blocked by tetrodotoxin. The suppression of the twitch response caused by lowering the Ca concn. or adding adenosine was effectively reversed by adding low concns. of aminopyridines. The aminopyridines also augmented the release of acetylcholine [51-84-3] from the resting ileum to about 3 to 10 times the control value. In contrast, tetraethylammonium did not influence the transmurally-stimulated or Ca-stimulated ileum. Thus, aminopyridines may act on cholinergic nerves in the ileum, causing increased release of acetylcholine by facilitating Ca movement rather than by blocking K conductance.

Detail of "16867-03-1"

2-Amino-3-hydroxypyridine

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