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Detail of "170902-47-3"

  • CAS Number:
  • 170902-47-3
  • Name:
  • L-Alanine,3-[[2-[(5R)-3-[4-(aminoiminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl]acetyl]amino]-N-(butoxycarbonyl)-,methyl ester

  • Molecular Structure:
  • Formula:
  • C21H29 N5 O6
  • Molecular Weight:
  • 447.4849
  • Synonyms:
  • L-Alanine,3-[[[(5R)-3-[4-(aminoiminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl]acetyl]amino]-N-(butoxycarbonyl)-,methyl ester (9CI); L-Alanine,3-[[[3-[4-(aminoiminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl]acetyl]amino]-N-(butoxycarbonyl)-,methyl ester, (R)-; DMP 755; Roxifiban
  • Density:
  • 1.35g/cm3
  • Boiling Point:
  • °Cat760mmHg
  • Flash Point:
  • °C

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CAS No.170902-47-3 L-Alanine,3-[[2-[(5R)-3-[4-(aminoiminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl]acetyl]amino]-N-(butoxycarbonyl)-,methyl ester

Roxifiban

Supplier:Shanghai Haoyuan Chemexpress Co., Ltd. [ China (Mainland)]

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Reference

Strategies for the manufacturing of some high potent anti-coagulants
Strategies for the manufacturing of some high potent anti-coagulants. Wennerberg, Johan; Granquist, Bo; Klingberg, Dan; Lindwall, Claudia; Sjoevall, Sven (Swed.). Chimica Oggi, 22(5), 18-20 (English) 2004 TeknoScienze. CODEN: CHOGDS. ISSN: 0392-839X. DOCUMENT TYPE: Journal; General Review CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 59 A review. Arterial occlusive disorders remain a major cause of mortality and morbidity in industrialized countries and, therefore, substances for their treatment are highly desired. In this article the authors describe the manufg. o 2 high potent anti-coagulants, namely roxifiban and warfarin, using different containment strategies. Roxifiban is synthesized via a convergent 10-step route where the last synthetic man' are performed using equipment containment. Warfarin which is a high vol. product, is synthesized in one step from com. available starting materials using area containment. A medical background is given together with description of the syntheses and a discussion about the different manufg. 81-81-2 and 170902-47-3 are just another two chemicals used in this study. strategies. .
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