Detail of "17397-93-2"

Reference

The antibacterial components of Dan-Shen

The antibacterial components of Dan-Shen. Fang, Chi-Nien; Chang, Pei-Ling; Hsu, Tsong-Pei (Inst. Mater. Med., Chin. Acad. Med. Sci., Peking, Peop. R. China). Hua Hsueh Hsueh Pao, 34(3), 197-209 (Chinese) 1976. CODEN: HHHPA4. ISSN: 0567-7351. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11, 3 Roots of Salvia miltiorrhiza (Dan-Shen) were extd. with ether, and the ext. was treated with 5% Na2CO3 to give a neutral fraction and a Na2CO3 fraction, followed by silica gel column chromatog. and thin-layer chromatog. The components sepd. were identified by UV, IR, and NMR spectrometry. Tanshinone I [568-73-0], tanshinone IIA [568-72-9], cryptotanshinone [35825-57-1], Me tanshinate [18887-19-9], hydroxytanshinone IIA [18887-18-8], tanshinone IIB [17397-93-2] and dihydrotanshinone I [20958-19-4] were detected in the neutral fraction, and 3 new compds. [danshexinkun A (I) [65907-75-7], danshexinkun B (II) [65907-76-8] and danshexinkun C (III) [65907-77-9]] were identified in the Na2CO3 fraction. Cryptotanshinone, dihydrotanshinone I, hydroxytanshinone IIA, Me tanshinate, and tanshinone IIB showed strong inhibitory activities against Staphylococcus aureus in vitro. Pharmaceutical prepns. contg. the compds. as active ingredients have been clin. applied.

Fatty emulsion injection containing tanshinone analogs for preventing or treating animal diseases and its preparation

All Rights Reserved. Fatty emulsion injection containing tanshinone analogs for preventing or treating animal diseases and its preparation.Several substances are used for example 17397-93-2 and 9004-53-9 which are their cas registry numbers. Zhang, Yumei (Arabela Pharmaceutical Holding (Tonghua) Co., Ltd., Peop. Rep. China). Faming Zhuanli Shenqing Gongkai Shuomingshu CN 1853624 A 1 Nov 2006, 23pp. (Chinese). (People's Republic of China). CODEN: CNXXEV. APPLICATION: CN 2010-67863 29 Apr 2005. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1 The present invention relates to compns. of fatty emulsion injection contg. tanshinone analogs for preventing or treating animal diseases and methods for its prepn. Each 1000 mL fatty emulsion contains 1.0-100.0 g tanshinone analogs. The fatty emulsion further contains subsidiary emulsifying agent, stabilizing agent, osmotic regulator, non-ionic surface active agent, gelatin, hydroxyethyl starch, propylene glycol, and glycerol. The tanshinone analogs are selected from one of cryptotanshinone, tanshinone IIA, sodium tanshinone IIA sulfonate, tanshinone IIB, sodium tanshinone IIB tanshinone, Me tanshinonate, tanshinaldehyde II, etc., or the mixt. thereof. Said vegetable oil is selected from one of soybean oil, maize oil, sunflower seed oil, peanut oil, sesame oil, and rape seed oil, or the mixt. thereof. Said phospholipid is selected from one of egg yolk lecithin, soybean lecithin, cephalin, hydrogenated egg yolk lecithin, and hydrogenated soybean lecithin, or the mixt. thereof. Said subsidiary emulsifying agent is selected from medium chain fatty glyceride. Said stabilizing agent is selected from cholesterol or phosphatidic acids. Said osmotic regulator is selected from albumin, dextrin, and ethylene polymer. The patent product has good stabilization and synergized action. .