Detail of "17422-74-1"

Reference

Chemistry of 4-oxo-4H-[1]benzopyran-3-carboxaldehyde

Chemistry of 4-oxo-4H-[1]benzopyran-3-carboxaldehyde. Ghosh, Chandra Kanta (Dep. Biochem., Calcutta Univ., Calcutta 700 019, India). J. Heterocycl. Chem., 20(6), 1437-45 (English) 1983. CODEN: JHTCAD. ISSN: 0022-152X. There are some commonly used reagents like 17422-74-1 in this article. DOCUMENT TYPE: Journal; General Review CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) A review with 81 refs. through 1982. .

In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone

All Rights Reserved. In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone. Nawrot-Modranka, Jolanta; Nawrot, Ewa; Graczyk, Julita (Department of Bioinorganic Chemistry, Faculty of Pharmacy, Medical University of Lodz, Lodz 90-151, Pol.). European Journal of Medicinal Chemistry, 41(11), 1301-1309 (English) 2006 Elsevier B.V. CODEN: EJMCA5. ISSN: 0223-5234. DOCUMENT TYPE: Journal CA Section: 29 (Organometallic and Organometalloidal Compounds) Section cross-reference(s): 1 The aim of this research was to examine chem. and biol. properties of the products of the reaction of Me chromone-3-carboxylate (2), 3-formyl-4-hydroxycoumarin (3), 3-formylchromone (6) and chromone 3-carbonyl chloride (7) with phosphorus hydrazides. For structure and keto-enol tautomerism analyses 1H, 13C, 31P NMR spectroscopy was used. The ring transformation species contg. the coumarin ring were predominant in the soln. The chromone series was obtained in reaction of phosphorus hydrazides with 3-formylchromone (6) and chromone-3-carbonyl chloride (7). Alkylating activity of phosphorohydrazides of coumarin and chromone was detd. with in vitro Preussmann test (NBP test). Some of the compds. were examd.There are some commonly used reagents with their cas registry numbers 93562-17-5 and 17422-74-1 in this article. towards antitumor and antibacterial activity. Some prepd. compds. demonstrated in vitro antitumor activity against P388 leukemia. Antineoplastic activity of the compds. combined with methotrexate was showed using L1210 murine leukemia. .